Results 81 to 90 of about 5,464,510 (283)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

LSTM-based maneuver detection for resident space object catalog maintenance

Neural Computing and Applications
Abstract Maintaining a catalog of Resident Space Objects involves a wide range of activities, exploiting measurement processing to estimate and update orbits, in an effort to achieve a comprehensive picture of the Near-Earth environment status in terms of human-made objects.
Riccardo Cipollone, Carolin Frueh, Pierluigi Di Lizia   +2 more
openaire   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

The Resident Space Object Detection Method Based on the Connection between the Fourier Domain Image of the Video Data Difference Frame and the Orbital Velocity Projection

Journal of Astronomy and Space Sciences
A method for resident space object detection in video stream processing using a set of matched filters has been proposed. Matched filters are constructed based on the connection between the Fourier spectrum shape of the difference frame and the ...
Vasilina Baranova, Alexander Spiridonov, Dmitrii Ushakov, Vladimir Saetchnikov   +3 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Attitude Motion Characterization of Resident Space Objects via Fusion of Ground-based and Space-based Light Curves

Due to the growing number of fragmentationrelated debris and the launch of mega constellations of satellites, the characterization of Resident Space Objects has been assuming a growing importance in the context of Space Situational Awareness programs to ...
Isoletta, Giorgio, Bencivenga, Pasquale, Opromolla, Roberto, Fasano, Giancarmine   +3 more
core   +1 more source

Space Domain Awareness Observations Using the Buckland Park VHF Radar

Remote Sensing
There is increasing interest in space domain awareness worldwide, motivating investigation of the use of non-traditional sensors for space surveillance. One such class of sensor is VHF wind profiling radars, which have a low cost relative to other radars
David A. Holdsworth, Andrew J. Spargo, Iain M. Reid, Christian L. Adami   +3 more
doaj   +1 more source

Operational Scheduling of Deep Space Radars for Resident Space Object Surveillance

, 2022
As space becomes increasingly congested and contested, new capabilities of rivals to threaten vital assets and exploit the area for military advantages make it more important than ever for the United States to proficiently track and monitor space traffic and debris.
openaire   +1 more source