Results 121 to 130 of about 1,134,808 (284)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Helping residents settle in residential aged care - Learnings from the PEARL study (Wellbeing Programs for Aged Care Residents Forum)

, 2019
Associate Professor Tanya Davison and Julie Kelly present findings from the PEARL project on assisting residents with adjustment to care.
Tanya Davison, Julie Kelly
core   +1 more source

A Skills-Based Curriculum for Outpatient Procedures in Internal Medicine Residency Training: Impact on Resident Confidence and Procedural Volume. [PDF]

Clin Teach
Keyserling K, Rusek M.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The Immunologic Basis, Neurological Manifestations and Management of the Anti Phospholipid Antibody Syndrome

Apollo Medicine, 2005
Monika Bradoo Raina, Namita Deka, Tsering P. Tashigang, Anoop Kohli   +3 more
doaj   +1 more source

Healthcare professionals' perceptions of participation and learning related to mealtimes in long-term care facilities: an interview study. [PDF]

BMC Geriatr
Allert C, Andersson S, Carlsson N, Sandgren A.   +3 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Aberrant Adrenal Tissue in Omentum: An Incidental Finding on Ovarian Cystectomy [PDF]

Journal of Clinical and Diagnostic Research, 2013
Meenu Pujani, Neha Kawatra Madan, Monisha Choudhury, Meenakshi Rao   +3 more
doaj   +1 more source

Closing the Gap Between Parental Leave Policy and Practice. [PDF]

Ann Fam Med
Cole S, Holder S, Le M.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source