Results 71 to 80 of about 4,280,025 (299)

DESENVOLVIMENTO E POLÍTICAS SOCIAIS FOCALIZADAS: DA CONCEPÇÃO DE ESTADO À CONCEPÇÃO DE MERCADO

Holos, 2017
O objeto de investigação do presente texto é a política social focalizada, em particular, busca demonstrar que as políticas sociais focalizadas não são apenas de cunho residual, podem ser ainda aliadas à políticas universalizantes, o que as tornam ...
Francisco Robert Bandeira Gomes da Silva, Antônia Jesuíta Lima   +1 more
doaj   +1 more source

Multiaxial validation of a finite element model of the intervertebral disc with multigenerational fibers to establish residual strain

JOR Spine, 2021
Finite element models of the intervertebral disc are used to address research questions that cannot be tested through typical experimentation.
Harrah R. Newman, John F. DeLucca, John M. Peloquin, Edward J. Vresilovic, Dawn M. Elliott   +4 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Investigations Exploring the Use of an Unstructured-Grid, Finite-Volume Modelling Approach to Simulate Coastal Circulation in Remote Island Settings—Case Study Region, Vanuatu/New Caledonia

Frontiers in Marine Science, 2021
Understanding coastal circulation and how it may alter in the future is important in island settings, especially in the South West Pacific, where communities rely heavily upon marine resources, and where sea level rise (SLR) is higher than the global ...
Serena Blyth Lee, Serena Blyth Lee, Fan Zhang, Charles James Lemckert, Charles James Lemckert, Rodger Tomlinson   +5 more
doaj   +1 more source

Least Squares Residuals and Minimal Residual Methods [PDF]

SIAM Journal on Scientific Computing, 2002
We study Krylov subspace methods for solving unsymmetric linear algebraic systems that minimize the norm of the residual at each step (minimal residual (MR) methods). MR methods are often formulated in terms of a sequence of least squares (LS) problems of increasing dimension. We present several basic identities and bounds for the LS residual.
Liesen, Jörg, Rozlozník, Miroslav, Strakoš, Zdeněk   +2 more
openaire   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Characterization of the Microstructure, Local Macro-Texture and Residual Stress Field of Commercially Pure Titanium Grade 2 Prepared by CONFORM ECAP

Metals, 2018
The paper investigated the residual strain and stress distribution, microstructure, and macro-texture along the transverse direction of commercially pure titanium grade 2 samples prepared by the CONFORM ECAP technique.
Gergely Németh, Klaudia Horváth, Charles Hervoches, Petr Cejpek, Jan Palán, Michal Duchek, Kristián Máthis   +6 more
doaj   +1 more source

Deep Residual Reinforcement Learning

, 2020
We revisit residual algorithms in both model-free and model-based reinforcement learning settings. We propose the bidirectional target network technique to stabilize residual algorithms, yielding a residual version of DDPG that significantly outperforms ...
Boehmer, Wendelin, Whiteson, Shimon, Zhang, Shangtong   +2 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data

Nature Communications, 2021
Intratumour heterogeneity (ITH) and mutational signatures are typically analysed separately, even though they are not necessarily independent. Here, the authors present CloneSig, a tool for the joint estimation of ITH and mutational signatures, with ...
Judith Abécassis, Fabien Reyal, Jean-Philippe Vert   +2 more
doaj   +1 more source