Results 71 to 80 of about 1,933,809 (317)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Characterization of the Microstructure, Local Macro-Texture and Residual Stress Field of Commercially Pure Titanium Grade 2 Prepared by CONFORM ECAP

Metals, 2018
The paper investigated the residual strain and stress distribution, microstructure, and macro-texture along the transverse direction of commercially pure titanium grade 2 samples prepared by the CONFORM ECAP technique.
Gergely Németh, Klaudia Horváth, Charles Hervoches, Petr Cejpek, Jan Palán, Michal Duchek, Kristián Máthis   +6 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data

Nature Communications, 2021
Intratumour heterogeneity (ITH) and mutational signatures are typically analysed separately, even though they are not necessarily independent. Here, the authors present CloneSig, a tool for the joint estimation of ITH and mutational signatures, with ...
Judith Abécassis, Fabien Reyal, Jean-Philippe Vert   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

The impact of different sprayable surfaces on the effectiveness of indoor residual spraying using a micro encapsulated formulation of lambda-cyhalothrin against Anopheles gambiae s.s [PDF]

, 2015
The type of sprayable surface impacts on residual efficacy of insecticide used in indoor residual spraying (IRS). However, there is limited data on common types of wall surfaces sprayed in Zanzibar and mainland Tanzania where IRS began in 2006 and 2007 ...
Jasper N Ijumba, Mwalimu, Charles D., Mwaipape, Osia, Juma G Rutta, Frances E Mugarula, Thawer, Narjis G., Stephen M Magesa, Jeremiah M Ngondi, Ramsan, Mahdi M., Ijumba, Jasper N., Fabrizio Molteni, Mahdi M Ramsan, Pratap, Harish B., Rutta, Juma G., Harish B Pratap, Molteni, Fabrizio, Narjis G Thawer, Ngondi, Jeremiah M., Mutagahywa, Joshua, Elias C Nyanza, Kafuko, Jessica M., Nyanza, Elias C., Reithinger, Richard, Mugarula, Frances E., Magesa, Stephen M., Osia Mwaipape, Isaiah Ndong, Charles D Mwalimu, Richard Reithinger, Jessica M Kafuko, Joshua Mutagahywa, Ndong, Isaiah   +31 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Residues of Manifolds

The Journal of Geometric Analysis, 2023
The Riesz $z$-energy of a manifold $X$ is the integration of the distance between two points to the power $z$ over the product space $X\times X$. Considered as a function of a complex variable $z$, it can be generalized to a meromorphic function by analytic continuation, which we will call the meromorphic energy function of $X$.
openaire   +3 more sources

Residual-versus-fitted plots.

, 2022
Residual-versus-fitted plots.
Seung-Whan Choi (10582466)
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source