Results 121 to 130 of about 1,389,226 (316)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Influência dos parâmetros de injeção na tensão residual e sua consequência no comportamento mecânico de componentes termoplásticos [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2014.As tensões residuais, inerentes a diversos processos de fabricação, na grande maioria dos casos não
Bianchezzi, Vinicius
core  

Residual Stress Analysis in both As-deposited and Annealed CrN Coatings

, 2005
In this paper, we report on residual stress analysis in physical vapour deposited (PVD) CrN coatings. Two 9 µm thick coatings were grown on tool steel substrates with bias voltages of - 50 V and -300 V, respectively.
Wang, Y D,, Peng, Ru,, Wang, Yan Dong,, Odén, Magnus,, Peng, Ru Lin,, Almer, Jon,, Almer, J,   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effect on Fatigue Performance of Residual Stress induced via Laser Shock Peening in Mechanically Damaged 2024‐T351 Aluminium Sheet [PDF]

, 2014
During manufacture and maintenance the fuselage skin of aircraft are susceptible to damage in the form of scratches. Normally not considered to be of major concern to aircraft structural integrity some airlines discovered fatigue cracks had initiated ...
Smyth, Niall
core  

A New Three-Parameter Flexible Unit Distribution and Its Quantile Regression Model

IEEE Access
This paper introduces a novel Poisson-unit-Weibull (PUW) distribution, which is defined on a unit domain and characterized by three parameters. The PUW distribution is capable of accommodating diverse non-monotone failure rates.
Mustapha Muhammad, Badamasi Abba, Jinsen Xiao, Najwan Alsadat, Farrukh Jamal, Mohammed Elgarhy   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Log Akash regression model with application

Songklanakarin Journal of Science and Technology (SJST)
The current study proposes and presents a new regression model for the response variable following the Akash distribution. The unknown parameters of the regression model are estimated using the maximum likelihood method. A simulation study is conducted
Samy Abd El Moez Mohamed, Ahmed Hassan Youssef, Salah Mahdy Ramadan, Amal Mohamed Abdelfattah   +3 more
doaj  

A new flexible extension of the generalized half-normal lifetime model with characterizations and regression modeling

Bulletin of Computational Applied Mathematics, 2018
In this paper, we introduced a new flexible extension of the Generalized Half-Normal lifetime model as well as a new log-location regression model based on the proposed model.
Haitham M. Yousof, G.G. Hamedani
doaj