Results 51 to 60 of about 90,452 (288)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Broad Diversity of Fungi in Hospital Water

The Scientific World Journal, 2020
Introduction. Some studies have reported the occurrence of microorganisms isolated from water. Considering these microorganisms, fungi are known to occur ubiquitously in the environment, including water, and some are pathogenic and may cause health ...
Máira Gazzola Arroyo, Adriano Menis Ferreira, Oleci Pereira Frota, Natalia Seron Brizzotti-Mazuchi, Jacqueline Tanury Macruz Peresi, Marcelo Alessandro Rigotti, Carlos Eduardo Macedo, Alvaro Francisco Lopes de Sousa, Denise de Andrade, Margarete Teresa Gottardo de Almeida   +9 more
doaj   +1 more source

Simulation and assessment of water supply network for specified districts at Najaf Governorate

Journal of the Mechanical Behavior of Materials, 2023
This study aims to simulate and assess the hydraulic characteristics and residual chlorine in the water supply network of a selected area in Al-Najaf City using WaterGEMS software.
Al-Mousawey Hassan Jaffar, Abed Basim Sh.   +1 more
doaj   +1 more source

Water quality in a reservoir used for carp production [PDF]

, 2002
Guadalupe Reservoir, on the San Cayetano river, feeds into the Lerma river about 18 km north of Toluca in the State of Mexico, Mexico. On August 9, 1995, more than 6000 Israeli carp (Cyprinus carpio v.
Abascal, Francisco, Abascal, Francisco, Bibiano Cruz, Luvina, Bibiano Cruz, Luvina, BULBULIAN GARABEDIAN, SILVIA, BULBULIAN GARABEDIAN, SILVIA, ESTELLER ALBERICH, MARIA VICENTA, ESTELLER ALBERICH, MARIA VICENTA, MARTINEZ MIRANDA, VERONICA, MARTINEZ MIRANDA, VERONICA   +9 more
core  

Intestinal antimicrobial gene expression: impact of micronutrients in malnourished adults during a randomized trial. [PDF]

, 2010
BACKGROUND: Because both micronutrients and antimicrobial peptides protect against diarrhea, we looked for an effect on intestinal antimicrobial peptide gene expression during a randomized controlled trial of multiple micronutrient (MM) supplementation ...
Bevins, Charles L, Dhaliwal, Winnie, Jagatiya, Poonam, Kelly, Paul, Khanam, Moriam, Ndulo, Namwiinga, Sanderson, Ian R, Shawa, Tamara, Simuyandi, Michelo   +8 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Modeling chlorine residuals in urban water distribution networks (Al-Ashrafieh – Homs)

Environmental Research Communications
Maintaining water quality in the water distribution networks has become a prominent issue. Chlorine Residual is an indicator to ensure water quality in the network A hydraulic analysis of the water distribution network in the Al-Ashrafieh city in Homs ...
Ruba D Alsaeed, Bassam Alaji, Lina Khouri   +2 more
doaj   +1 more source

Monitoring Residual Chlorine Decay and Coliform Contamination in Water Distribution Network of Kampala, Uganda

Journal of Applied Sciences and Environmental Management, 2011
The study was undertaken to examine water quality in the distribution network of Kampala City by assessing five storage reservoirs and four consumer taps.
J Ecura, J Okot-Okumu, TO Okurut
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Relationship between chlorine decay and nanobubble application in secondary treated wastewater

Water Science and Technology
There has been numerous research on the uses of treated wastewater that needs chlorine disinfection, but none have looked at the impacts of injecting nanobubbles (NBs) on the decomposition of residual chlorine.
Ahmed Khaled Abdella Ahmed, Moussa Shalaby, Osama Negim, Talaat Abdel-Wahed   +3 more
doaj   +1 more source