Results 71 to 80 of about 90,434 (287)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Relationship between Turbidity and Residual Chlorine and Microbial Quality of Drinking Water

open access: yesMedical Laboratory Journal, 2014
Background and Objective: Safe drinking water is essential for health and health promotion is dependent on providing safe water. We aimed to determine the relationship between turbidity & residual chlorine and microbial quality of drinking water in Agh ...
A Zafarzadeh, N Amanidaz, N Seyedghasemi
doaj  

Calibration and comparison of chlorine decay models for a test water distribution system [PDF]

open access: yes, 2000
This paper investigates the kinetics of monochloramine as disinfectant in a 1.3 km water pipe. A novel procedure for the correction of chlorine meter errors is introduced and applied.
Maier, S, Powell, R S, Woodward, C A
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Hygiene status and influencing factors of swimming venues: Based on surveillance data from 2010 to 2024 in Shanghai

open access: yes环境与职业医学
BackgroundSwimming is becoming increasingly popular for its combined leisure and fitness benefits. However, polluted swimming pool water may pose various health risks.
Fengchan HAN   +8 more
doaj   +1 more source

Reduced Chlorine in Drinking Water Distribution Systems Impacts Bacterial Biodiversity in Biofilms

open access: yesFrontiers in Microbiology, 2018
In drinking water distribution systems (DWDS), a disinfectant residual is usually applied to limit bacterial regrowth. However, delivering water with no or reduced chlorine residual could potentially decrease the selection for antimicrobial resistant ...
Claire Bertelli   +7 more
doaj   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

Comparing a microbial biocide and chlorine as zebra mussel control strategies in an Irish drinking water treatment plant [PDF]

open access: yes, 2013
A need exists for an environmentally friendly mussel control method to replace chlorine and other traditional control methods currentlyutilised in drinking water plants and other infested facilities.
Bridget Gruber   +3 more
core   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

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