Results 121 to 130 of about 832 (155)

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Impact of N-heterocyclic amine modulators on the structure and thermal conversion of a zeolitic imidazole framework. [PDF]

J Mater Chem A Mater
Castells-Gil J, Zhu J, Itskou I, Wolpert EH, Hunter RD, Tidey JP, Pedersen A, Solvay E, Tyrrell H, Petit C, Barrio J.   +10 more
europepmc   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

Chemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Self‐assembly and Lateral Cobalt Coordination of a Fivefold Symmetric Cyanostar Macrocycle on an Au(111) Surface

Chemistry – A European Journal, EarlyView.
Herein, we report the first example of the formation of a close‐packed, regular 2D monolayer of a fivefold symmetric cyanostar macrocycle on an Au(111) surface under ultra‐high vacuum and the structural modification of such self‐assembled architecture upon cobalt atom deposition.
Lenka Černá, Miguel Martínez García, Shanmugasibi K. Mathialagan, Sofía O. Parreiras, Koen Lauwaet, José Ignacio Urgel, Aurelio Gallardo, Amar H. Flood, Tomás Torres, José M. Gallego, Giovanni Bottari, David Écija   +11 more
wiley   +1 more source

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Regulating antimicrobial resistance in the environment: analysis of Thailand legal framework and areas for reinforcement. [PDF]

Sci One Health
Lekagul A, Khotchalai S, Kaewkhankhaeng W, Gordoncillo M, Utrarachkij F, Tangcharoensathien V.   +5 more
europepmc   +1 more source

Morphological Control of Aurophilic Chains of Gold(I) Dithiolate Dimers With Alkali and Alkali Earth Cations

Chemistry – A European Journal, EarlyView.
Luminescent coordination polymers of Group 1 (Li, K, Cs) and 2 (Mg─Ba) cations with gold(I) iso‐maleonitriledithiolate ({Au2[S2C = C(CN)2]}2−) units were prepared; 1‐D aurophilic chains are present in all cases. The structures strongly depend on cation charge and size, with N‐cyano coordination observed in the Gp 1 and larger Gp 2 cations. Increasingly
Jefferson A. Pells, William W. L. Ho, Daniel B. Leznoff   +2 more
wiley   +1 more source

Environmentally friendly synthesis of quantum dots and their applications in diverse fields from the perspective of environmental compliance: A review. [PDF]

Discov Nano
He H, Deng S, Liu Y.
europepmc   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Cyanide overproduction impairs cellular bioenergetics in Down syndrome. [PDF]

Neurotherapeutics
Petrosino M, Zuhra K, Kieronska-Rudek A, Janickova L, Bremer O, Khalaf M, Logue BA, Szabo C.   +7 more
europepmc   +1 more source