Results 161 to 170 of about 6,667,826 (304)

Predictors of posttransplant measurable residual disease negativity and impact on clinical outcomes in multiple myeloma. [PDF]

Blood Adv
Bolarinwa A, Zanwar S, Abdallah N, Nagaraj M, Seth S, Buadi FK, Hayman SR, Gertz MA, Dispenzieri A, Muchtar E, Kapoor P, Gonsalves W, Kourelis T, Dingli D, Warsame R, Leung N, Cook J, Binder M, Lin Y, Hwa L, Rogers MG, Hobbs M, Fonder A, Jevremovic D, Rajkumar SV, Kumar SK.   +25 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Residual disease activity in cystic fibrosis lung disease: implications for clinical management and research. [PDF]

Am J Respir Crit Care Med
Gramegna A, Putti G, Alicandro G, Mall MA, Blasi F.   +4 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

ctDNA-based detection of residual disease: implications for management of non-metastatic NSCLC. [PDF]

Front Oncol
Leclercq C, Wespiser M, Tachon G, Buisson A, Pérol M, Swalduz A.   +5 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

FLT3-ITD Measurable Residual Disease in Acute Myeloid Leukemia: Recommended, but Not Yet Self-Sufficient. [PDF]

Hematol Oncol
Albano F.
europepmc   +1 more source

DDT residual spray operations

This manual describes the operations of the Extended Malaria Control Program which utilizes residual DDT spraying of homes as a method of malaria control.

core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source