Results 101 to 110 of about 390,506 (291)

Fast demagnetization method for power transformers combined with residual flux measurement

International Journal of Electrical Power & Energy Systems
When power transformers are re-energized, the inrush current may be generated and damage electrical equipment. In order to suppress the generation of serious inrush current, the residual flux (RF) in the power transformer core needs to be eliminated ...
Yuzhan Ren, Chengcheng Liu, Youhua Wang
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Flux-vector splitting and Runge-Kutta methods for the Euler equations [PDF]

Runge-Kutta schemes have been used as a method of solving the Euler equations exterior to an airfoil. In the past this has been coupled with central differences and an artificial vesocity in space.
Turkel, E., Vanleer, B.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The influence of river discharge on energy transport in estuaries and its implication for the equilibrium bed profile

Engineering Applications of Computational Fluid Mechanics
In this paper, we revisit the classical energy transport equation for pure tidal flows in estuaries by including the effects of residual water level and freshwater discharge.
Min Zhang, Bo Li, Tianyi Xie, Ian Townend, Tongtiegang Zhao, Huayang Cai   +5 more
doaj   +1 more source

A semi-empirical model of the energy balance closure in the surface layer.

PLoS ONE, 2018
It has been hypothesized that the energy balance closure problem of single-tower eddy-covariance measurements is linked to large-scale turbulent transport. In order to shed light on this problem, we investigate the functional dependence of the normalized
Frederik De Roo, Sha Zhang, Sadiq Huq, Matthias Mauder   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

On the Connection between Residual Distribution Schemes and Flux Reconstruction

, 2018
In this short paper, we are considering the connection between the \emph{Residual Distribution Schemes} (RD) and the \emph{Flux Reconstruction} (FR) approach. We demonstrate that flux reconstruction can be recast into the RD framework and vice versa. Because of this close connection we are able to apply known results from RD schemes to FR methods.
Abgrall, Remi, Meledo, Elise le, Oeffner, Philipp   +2 more
openaire   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source