Results 51 to 60 of about 112,777 (261)

Diagnostics in time series analysis [PDF]

open access: yes, 1994
The portmanteau diagnostic test for goodness of model fit is studied. It is found that the true variances of the estimated residual autocorrelation function are potentially deflated considerably below their asymptotic level, and exhibit high correlations
Warnes, Alexis, Warnes, A
core  

Solution of the Fractional Bratu-Type Equation Via Fractional Residual Power Series Method

open access: yesTatra Mountains Mathematical Publications, 2020
Abstract In this paper, we present numerical solution for the fractional Bratu-type equation via fractional residual power series method (FRPSM). The fractional derivatives are described in Caputo sense. The main advantage of the FRPSM in comparison with the existing methods is that the method solves the nonlinear problems without ...
Khalouta, Ali, Kadem, Abdelouahab
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A comparative study on residual power series method and differential transform method through the time-fractional telegraph equation

open access: yesNonlinear Engineering
In the present era of cutting-edge technologies powering electronic devices, energy systems, and modern telecommunication, a mathematical model called the telegraph equation plays a major role. It describes the wave propagation and diffusion processes in
Devshali Pratiksha, Singh Prince
doaj   +1 more source

Computational study for the conformable nonlinear Schrödinger equation with cubic–quintic–septic nonlinearities

open access: yesResults in Physics, 2021
The fractional (3+1)-dimensional nonlinear Schrödinger equation with cubic–quintic–septic nonlinearities plays a significant role in the study of ultra-short pulses in highly nonlinear optical phenomena.
Hira Tariq   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Toward computational algorithm for time-fractional Fokker–Planck models

open access: yesAdvances in Mechanical Engineering, 2019
This article describes an efficient algorithm based on residual power series to approximate the solution of a class of partial differential equations of time-fractional Fokker–Planck model. The fractional derivative is assumed in the Caputo sense.
Asad Freihet   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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