Results 61 to 70 of about 763,518 (232)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

On the solutions of fractional random ordinary differential equations with the Residual power series method

Alexandria Engineering Journal, 2023
In this study, random ordinary differential equations obtained by randomly choosing the coefficients or initial conditions of the ordinary differential equations will be analyzed by the Residual Power Series Method. The initial conditions or coefficients
Mehmet Merdan, Nihal Atasoy
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A Numerical Solution of Fractional Lienard’s Equation by Using the Residual Power Series Method

Mathematics, 2017
In this paper, we investigate a numerical solution of Lienard’s equation. The residual power series (RPS) method is implemented to find an approximate solution to this problem.
Muhammed I. Syam
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Spectroscopic study of the O-type runaway supergiant HD 195592

, 2009
The scope of this paper is to perform a detailed spectroscopic study of the northern O-type supergiant HD 195592. We use a large sample of high quality spectra in order to investigate its multiplicity, and to probe the line profile variability.
Blaauw, Conti, De Becker, De Becker, De Becker, de Wit, Fullerton, G. Rauw, Gillet, Gosset, Heck, Kambe, Kaufer, Kay, Leonard, M. De Becker, Martins, Mason, McSwain, N. Linder, Noriega-Crespo, Plaskett, Portegies Zwart, Rauw, Rauw, Schilbach, Zwicky   +26 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Numerical Investigation to Fuzzy Volterra Integro-Differential Equations via Residual Power Series Method

ASM Science Journal, 2020
In this paper, a study of a numerical approximate solution to fuzzy Volterra integro-differential equations is presented under strongly generalised differentiability by applying an influent effective technique, called the Residual Power Series (RPS ...
Mohammad Alshammari
doaj   +1 more source

Fractional View Analysis System of Korteweg–de Vries Equations Using an Analytical Method

Fractal and Fractional
This study introduces two innovative methods, the new transform iteration method and the residual power series transform method, to solve fractional nonlinear system Korteweg–de Vries (KdV) equations.
Yousef Jawarneh, Zainab Alsheekhhussain, M. Mossa Al-Sawalha   +2 more
doaj   +1 more source