Results 101 to 110 of about 3,340,374 (282)

Simulation of vessel tissue remodeling with residual stress: an application to in-stent restenosis

International Journal of Smart and Nano Materials, 2019
We present a numerical procedure to model the artery wall remodeling stimulated by stenting considering varying degree of residual stresses. This framework sets up biological remodeling with the existence of residual stress. Previous studies suggest that
Jie Cheng, Lucy T. Zhang
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Finite element analysis of localised rolling to reduce residual stress and distortion [PDF]

, 2013
Fusion welding processes cause residual stress due to the uneven heat distribution produced by the moving welding torch. These residual stresses are characterised by a large tensile component in the welding direction.
Cozzolino, Luis D.
core   +3 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

How Atomic Bonding Plays the Hardness Behavior in the Al–Co–Cr–Cu–Fe–Ni High Entropy Family

Small Science
A systematic study on a face‐centered cubic‐based compositionally complex alloy system Al–Co–Cr–Cu–Fe–Ni in its single‐phase state is carried out, where a mother senary compound Al8Co17Cr17Cu8Fe17Ni33 and five of its suballoys, obtained by removing one ...
Andrea Fantin, Giovanni O. Lepore, Michael Widom, Sergey Kasatikov, Anna M. Manzoni   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

An integrated approach to the determination and consequences of residual stress on the fatigue performance of welded aircraft structures [PDF]

, 2005
Although residual stress in welded structures and components has long been known to have an effect on their fatigue performance, access to reliable, spatially accurate residual stress field data has been limited.
Edwards, Lyndon, Fitzpatrick, Michael E., Yapp D, Yapp, D, Sinclair, I, Fitzpatrick, M. E., Sinclair, I., Edwards L, Sinclair I, Edwards, L, Zhang, X, Zhang, Xiang, Irving, P. E., Irving, Phil E., Fitzpatrick M E, Fitzpatrick ME, Irving PE, Zhang X, Irving P E, Yapp, David   +19 more
core   +1 more source

Welding Temperature Field and Residual Stress Analysis of Multi-box Single-cell Steel Girder

Zhongying He, Zihan Guo, Shuguang Wu, Haihai Wu, Shaowei Ma, Zhengyuan Zhang, Junhong Yin   +6 more
  +5 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source