Results 121 to 130 of about 3,927,680 (242)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
This study aims to observe the residual stress in a substrate and predict stress behavior during the laser deposition process (DED) using finite element analysis (FEA). The residual stress observed on the substrate surface indicated that stress variation
Su Seong Woo +3 more
doaj +1 more source
Residual stresses in bulk ceramics
S.274-285Residual stresses in ceramics are of interest for two reasons. First, residual stresses are superimposed on external stresses and thus influence the service behavior of the machined parts.
Pfeiffer, W.
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Study on residual stress and strain during rail rolling contact of straight U75V rail
The distribution of residual stress produced by straightening process in side the rail is obtained. And then the residual stress result is used as the initial condition to study the stress and strain variation rule of wheel-rail rolling contact process ...
M. X. Gao, H. Song, J. Yang, L. J. Fu
doaj
Welding residual stress is related to the mechanical properties and service life of components. To accurately grasp the residual stress distribution of thick plate 2219 aluminum alloy after friction stir welding (FSW), optimize the welding process, and ...
WANG Binrong
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source

