Results 141 to 150 of about 419,786 (311)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Film residual stress assessment method via temporarily thermal relaxation [PDF]
, 2013 The concept of temporarily thermal relaxation is extended theoretically to assess the film residual stress. First, the contribution of the initial stress to the observable displacement field is separated with eliminating the thermal expansion effect of ...
Chen-wu Wu, 吴臣武, 程欣欣
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Study on residual stress and strain during rail rolling contact of straight U75V rail
Metalurgija, 2019 The distribution of residual stress produced by straightening process in side the rail is obtained. And then the residual stress result is used as the initial condition to study the stress and strain variation rule of wheel-rail rolling contact process ...
M. X. Gao, H. Song, J. Yang, L. J. Fu
doaj
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Investigation of thermal techniques to mitigate buckling distortion in welding panels [PDF]
, 2012 This thesis describes the advancements of the application of thermal tensioning techniques to different weld geometries in order to eliminate buckling distortion.
Nagy, T.
core
Modelling of ultrasonic impact treatment (UIT) of welded joints and its effect on fatigue strength
Fracture and Structural Integrity, 2015 Ultrasonic impact treatment (UIT) is a remarkable post-weld technique applying mechanical impacts in combination with ultrasound into the welded joints. In the present work, a 3D simulation method including welding simulation, numerical modelling of UIT ...
K.L. Yuan, Y. Sumi
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Measurement and modelling of the transient thermal-mechanical strain field during GMA welding [PDF]
, 2011 The state of residual stress in welded joints is a well-studied topic, and many methodsof residual stress measurement are now available. However, far less is known aboutthe transient strains which occur during the welding process, even though these ...
Colegrove, Paul A. +3 more
core