Results 151 to 160 of about 3,340,374 (282)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

RESIDUAL STRESS ANALYSIS OF UNCOOLED INFRARED FOCAL PLANE ARRAYS BY MICRO-RAMAN SPECTROSCOPY

Jixie qiangdu, 2015
The uncooled infrared focal plane arrays（ UIRFPA） used in this micro-Raman experiment are composed of Si O2 thin film and Si substrate. They have the characteristic of MEMS microstructure.
CEN Hao, WANG KeYong
doaj  

Residual-based ARIMA_CNN_LSTM modeling for borehole stress time-series forecasting [PDF]

Jun Tang, Ting, Guolin Guo, Li Liu, Shuxin Ni   +4 more
openalex   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Analysis of Thermal Residual Stresses in TiC Coatings on Gradient Cemented Carbide

工程科学与技术, 2012
: Thermal residual stresses in two models of TiC coating cemented carbide with and without a gradient layer were calculated using the finite element method.
Qin Kang-cai
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The effect of microstructure and residual stress on crack propagation in engineering ceramics

Ebru Karakurt Uluscu
openalex   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Correlating energy density induced residual stress, porosity, and mechanical property variations in directed energy deposition using neutron diffraction and imaging techniques

Journal of Materials Research and Technology
Chuting Tsai, Xinchang Zhang, W. Chuirazzi, Cheng Sun, Jeffrey R. Bunn, Yuxuan Zhang, M. Matos, E. Payzant   +7 more
semanticscholar   +1 more source

Experimental Evidence for the Impact of Copper Microstructure on Residual Stress of Through Silicon Via

Shuhang Lyu, Thomas E. Beechem, Tiwei Wei   +2 more
openalex   +1 more source