Results 241 to 250 of about 126,866 (295)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Electrohydrodynamic printing technology: mechanisms, control, and applications. [PDF]

open access: yesMicrosyst Nanoeng
Tian Y   +6 more
europepmc   +1 more source

Towards Closed-Loop Neuromodulation for Type 2 Diabetes With Ex Vivo Validation of Beta-Cell Activity and FOPP Detection. [PDF]

open access: yesIEEE Trans Biomed Circuits Syst
Eskandari R   +8 more
europepmc   +1 more source

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