Results 141 to 150 of about 654,490 (307)

Mutation of an Active Site Residue of Tryptophan Synthase (β-Serine 377) Alters Cofactor Chemistry [PDF]

, 1998
Kwang-Hwan Jhee, Lihong Yang, Salman Ahmed, Peter McPhie, Roger S. Rowlett, Edith Wilson Miles   +5 more
openalex   +1 more source

Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry

, 2023
Ross P. Thomas, Emma K. Grant, Eleanor R. Dickinson, Francesca Zappacosta, Lee J. Edwards, Michael M. Hann, David House, Nicholas C. O. Tomkinson, Jacob T. Bush   +8 more
openalex   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Effect of plant residue and water management practices on soil redox chemistry, methane emission, and rice productivity

, 2004
Manoch Kongchum
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Residual Characteristics and Processing Factors of Flubendiamide and Tebufenozide in Rice and Its Processed Products

Foods
This study aimed to evaluate residue changes in flubendiamide and tebufenozide during the processing of whole grain into milled rice, cooked rice, and rice cake, and to calculate their processing factors (PFs).
Dongju Kim, Eunbeen Oh, Seunghyeon Jo, Hyeonwoo Shin, Youngjin Ham, Junyoung Kim, Mihyun Cho, Moohyeog Im, Keesung Kyung   +8 more
doaj   +1 more source

Effects of Zinc Supplementation on Laying Performance, Serum Chemistry and Zn Residue in Tibia Bone, Liver, Excreta and Egg Shell of Laying Hens [PDF]

, 2011
O. M. O. Idowu, Olawale Razaq Ajuwon, A. O. Oso, O. A. Akinloye   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

ACS AMA: Hi, Reddit! I am Dr. Suzanne Bell, Chair of the Department of Forensic and Investigative Science at West Virginia University. Ask me anything about the chemistry of gunshot residue or educational opportunities in forensic chemistry.

, 2017
AmerChemSocietyAMA, r Science
openalex   +1 more source