Results 21 to 30 of about 2,532,187 (254)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

EXPERIMENTAL DEFINITION OF RESIDUAL STRESSES IN CONCRETE CONSTRUCTIONS

Bridges and tunnels: Theory, Research, Practice, 2015
Purpose. Relevant for bridges, which are operated, is a matter of determining the stress state of the structures standing loads. To solve this problem is proposed to determine the stress specified by the nonessential local destruction, which need to be improved. Methodology.
openaire   +2 more sources

Definition of Residue Theorem and its Basic Applications

Highlights in Science, Engineering and Technology, 2023
This paper explains the fundamentality of residue theorem in complex analysis integration termed contour integral. It also illustrates the importance of this theorem, followed by applying it in both mathematics and other fields where several typical examples coming from different fields are chosen.
openaire   +1 more source

Applying Residue Theorem to Compute Real Definite Integral

Journal of Physics: Conference Series, 2021
Abstract The Residue Theorem is one of the fundamental theorems in complex analysis. It can be used to integrate some types of real functions that are difficult, or even unable, to be expressed in terms of fundamental functions. This paper reevaluates the application of the Residue Theorem in the real integration of one type of function ...
Nanru Dai, Yunxing Zhang
openaire   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

An alternative definition of tense operators on residuated lattices

Journal of Logic and Computation
Abstract In this paper, we introduce and study an alternative definition of tense operators on residuated lattices. We give a categorical equivalence for the class of tense ICRDL-algebras, which is motivated by an old construction by J. Kalman.
Ismael Calomino, Gustavo Pelaitay, William Javier Zuluaga Botero   +2 more
openaire   +3 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

On Cox and Snell's General Definition of Residuals

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1969
Summary Cox and Snell have introduced a definition of residuals, in a situation more general than the usual linear hypothesis. They have also discussed briefly the distribution of these residuals, and the complementary aspect of transforming them so that they have (approximately) the same distribution as the random variables which they ...
openaire   +2 more sources

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source