Results 51 to 60 of about 409,543 (262)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Transdiagnostic psychosocial interventions to promote mental health in forcibly displaced persons: a systematic review and meta-analysis

European Journal of Psychotraumatology, 2023
Background: People forced to leave their homes, such as refugees and internally displaced persons, are exposed to various stressors during their forced displacement, putting them at risk for mental disorders.
Sarah K. Schäfer, Angela M. Kunzler, Saskia Lindner, Jan Broll, Marlene Stoll, Jutta Stoffers-Winterling, Klaus Lieb   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Resilience and Transformation of University Waste Management During COVID-19: A Case Study of Shahid Sadoughi University of Medical Sciences, Yazd [PDF]

Journal of Environmental Health and Sustainable Development
Introduction: Universities are concentrated hubs of waste generation, and the COVID-19 pandemic has profoundly reshaped waste management dynamics. This study investigated the resilience and transformation of campus waste streams at Shahid Sadoughi ...
Parvin Zamani, Masoomeh Bagheri, Mehdi Mokhtari, Ehsan Abouee Mehrizi, Mehdi Sarlak, Masoume Javaheri, Mehran Yazdandoust   +6 more
doaj  

Assessment of the resilience and long-term effects of climate change on the surface area of Lake Yojoa

Sustainable Environment
Lake Yojoa is Honduras’s only natural freshwater lake with historical, cultural, and recreational value. The lake is the core of the local economy and one of the country’s biggest tourist attractions.
Alexander David Reyes-Avila, Riley Ann Baxter   +1 more
doaj   +1 more source

A Theory of Transformative Agency in Linked Social-Ecological Systems

Ecology and Society, 2013
We reviewed the literature on leadership in linked social-ecological systems and combined it with the literature on institutional entrepreneurship in complex adaptive systems to develop a new theory of transformative agency in linked social-ecological ...
Frances R. Westley, Ola Tjornbo, Lisen Schultz, Per Olsson, Carl Folke, Beatrice Crona, Örjan Bodin   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Análise da estrutura e da diversidade de uma vegetação ciliar do rio São Francisco, Petrolina–PE. Structure and diversity analysis of a São Francisco river banks vegetation, Petrolina–PE. [PDF]

Revista do Instituto Florestal, 2010
No pólo agrícola Petrolina–PE/Juazeiro–BA é grande a devastação das matas ciliares do rio São Francisco, devido à expansão da agricultura irrigada.
Silvana Cristina Pereira Muniz de SOUZA, Paulo César Fernandes LIMA, Bruno Almozara ARANHA   +2 more
doaj