Results 31 to 40 of about 451,065 (288)

Resilience [PDF]

AMA Journal of Ethics, 2018
When I told people I was pursuing a career in medicine, the statistics of female physician suicide were mentioned. When I professed an interest in surgery, I was told to choose a specialty for lifestyle, because as a woman I would need a career that would allow me to raise my future children.
openaire   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Enhancing the Fit through Adaptive Co-management: Creating and Maintaining Bridging Functions for Matching Scales in the Kristianstads Vattenrike Biosphere Reserve, Sweden

Ecology and Society, 2007
In this article, we focus on adaptive governance of social-ecological systems (SES) and, more specifically, on social factors that can enhance the fit between governance systems and ecosystems. The challenge lies in matching multilevel governance system,
Per Olsson, Carl Folke, Victor Galaz, Thomas Hahn, Lisen Schultz   +4 more
doaj   +1 more source

Measurement of Resilience and the Time Value of Resilience [PDF]

IEEE Systems Journal, 2021
In prior work, a measure of resilience for use in systems design and management was presented. The measure has the form of a time integral of the system performance level. This form generates the research question: Is the time value of resilience a meaningful concept, like the time value of money in engineering economics.
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Digital interventions to promote psychological resilience: a systematic review and meta-analysis

npj Digital Medicine
Societies are exposed to major challenges at an increasing pace. This underscores the need for preventive measures such as resilience promotion that should be available in time and without access barriers.
Sarah K. Schäfer, Lisa von Boros, Lea M. Schaubruch, Angela M. Kunzler, Saskia Lindner, Friederike Koehler, Tabea Werner, Federico Zappalà, Isabella Helmreich, Michèle Wessa, Klaus Lieb, Oliver Tüscher   +11 more
doaj   +1 more source

The problem of spatial fit in social-ecological systems: detecting mismatches between ecological connectivity and land management in an urban region

Ecology and Society, 2014
The problem of institutional fit in social-ecological systems has been empirically documented and conceptually discussed for decades, yet there is a shortage of approaches to systematically and quantitatively examine the level of fit. We address this gap,
Arvid Bergsten, Diego Galafassi, Örjan Bodin   +2 more
doaj   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

QAnon Conspiracy Theory: Examining its Evolution and Mechanisms of Radicalization

Journal for Deradicalization, 2021
This report demonstrates the overarching need for additional exploration and intervention of conspiracy-based radicalization as the QAnon conspiracy theory continues to grow.
Amanda Garry, Samantha Walther, Rukaya Rukaya, Ayan Mohammed   +3 more
doaj  

Photovoice for mobilizing insights on human well-being in complex social-ecological systems: case studies from Kenya and South Africa

Ecology and Society, 2018
The value of diverse perspectives in social-ecological systems research and transdisciplinarity is well recognized. Human well-being and how it is derived from dynamic ecosystems is one area where local knowledge and perspectives are critical for ...
Vanessa A. Masterson, Shauna L. Mahajan, Maria Tengö   +2 more
doaj   +1 more source