Results 51 to 60 of about 1,677,724 (305)

Enhancing the Fit through Adaptive Co-management: Creating and Maintaining Bridging Functions for Matching Scales in the Kristianstads Vattenrike Biosphere Reserve, Sweden

open access: yesEcology and Society, 2007
In this article, we focus on adaptive governance of social-ecological systems (SES) and, more specifically, on social factors that can enhance the fit between governance systems and ecosystems. The challenge lies in matching multilevel governance system,
Per Olsson   +4 more
doaj   +1 more source

Strengths, Narrative, and Resilience: Restorying Resilience Research [PDF]

open access: yes, 2016
Objective: To envision a path toward a more strengths-based approach to violence research, prevention, and intervention—a path that focuses on thriving and resilience.
Banyard, Victoria   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Resilient connections

open access: yesVITRUVIO - International Journal of Architectural Technology and Sustainability, 2021
The paper presents Axis Strutture, patented by the authors, awarded with V:alere funds (VAnvitelli pER la ricErca 2020) for the establishment of an innovative start-up, now academic spin-off. It is based on the assemble of iron and wood with 'pins' (in Latin 'axis') threaded to ensure an economic profit in line with the Sustainable Development Goals ...
Rossi, Adriana, Sara Gonizzi Barsanti
openaire   +6 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A review of marine genetic resource valuations

open access: yesnpj Ocean Sustainability
Marine biotechnology is a rapidly growing sector of the ocean economy, but efforts to assess its value, and that of the genetic resources that enable it, remain contentious.
Tilde Krusberg   +4 more
doaj   +1 more source

Photovoice for mobilizing insights on human well-being in complex social-ecological systems: case studies from Kenya and South Africa

open access: yesEcology and Society, 2018
The value of diverse perspectives in social-ecological systems research and transdisciplinarity is well recognized. Human well-being and how it is derived from dynamic ecosystems is one area where local knowledge and perspectives are critical for ...
Vanessa A. Masterson   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

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