Results 61 to 70 of about 770,190 (313)

Definitions of Disturbance, Resilience and Robustness in ATM Context [PDF]

open access: yes, 2012
Resilience is a fundamental property of the natural ecosystem that enables quick recovery after numerous disturbances occurring frequently. This vital ability of the ecosystem makes resilience a very desirable property of man-made socio-technical ...
Gluchshenko, Olga
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Assessing the role of non-state actors in health service delivery and health system resilience in Myanmar

open access: yesInternational Journal for Equity in Health
Background Due to the weaknesses of the public health system and its low reach, especially in border areas, provision of health services by non-state actors (NSAs) has historically played an important role in Myanmar. NSAs include local and international
K. Than   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Working as one: a road map to disaster resilience for Australia [PDF]

open access: yes, 2014
This report offers a roadmap for enhancing Australia’s disaster resilience, building on the 2011 National Strategy for Disaster Resilience. It includes a snapshot of relevant issues and current resilience efforts in Australia, outlining key challenges ...
Paul Barnes   +5 more
core  

Don't sweat the small stuff: Understanding teacher resilience at the chalkface [PDF]

open access: yes, 2012
This study investigates how graduating and early career teachers perceive resilient teachers. Informed by survey data from 200 graduating and early career teachers, the study's results indicate that graduating and early career teachers perceive that ...
Price, A.   +11 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Clarifying Resilience: an invited comment [PDF]

open access: yes, 2013
So, we all know what resilience is, don’t we? The National Academies recently said building disaster resilience capacity in our communities should be a national imperative (National Academies 2012).So resilience must be a tangible thing ...
Deeming, Hugh
core  

Resilience: Accounting for the Noncomputable [PDF]

open access: yes, 2009
Plans to solve complex environmental problems should always consider the role of surprise. Nevertheless, there is a tendency to emphasize known computable aspects of a problem while neglecting aspects that are unknown and failing to ask questions about ...
Carl Folke   +11 more
core   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

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