Results 31 to 40 of about 453,408 (276)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
South Asia and societal challenges : a regional perspective [PDF]
, 2015 This paper is a summary of the South Asian region’s status and interests concerning the seven thematic societal challenges identified under the EU’s Horizon 2020 research programme: Health, demographic change and wellbeing; Food security, sustainable ...
Amaratunga, Dilanthi +3 more
core
Borneo coral reefs subject to high sediment loads show evidence of resilience to various environmental stressors [PDF]
, 2019 For reefs in South East Asia the synergistic effects of rapid land development, insufficient environmental policies and a lack of enforcement has led to poor water quality and compromised coral health from increased sediment and pollution.
Braoun, Christina +4 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Accredited qualifications for capacity development in disaster risk reduction and climate change adaptation [PDF]
, 2016 Increasingly practitioners and policy makers working across the globe are recognising the importance of bringing together disaster risk reduction and climate change adaptation. From studies across 15 Pacific island nations, a
Buliruarua, Leigh-Ann +20 more
core
Nutritient flow scenarios for sustainable smallholder faming systems in southwestern Burkino Faso : food security and better livelihoods for rural dryland communities [PDF]
, 2017 The report presents a study on nutrient flows of agricultural livelihood systems dominated by smallholder farms in South-western Burkina Faso. The material flow analysis of nitrogen, phosphorus, and potassium provides a detailed picture of current ...
Boundia, Alexandre Thiombiano +2 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Buckling of Carbon Nanotubes: A State of the Art Review
, 2011 The nonlinear mechanical response of carbon nanotubes, referred to as their "buckling" behavior, is a major topic in the nanotube research community. Buckling means a deformation process in which a large strain beyond a threshold causes an abrupt change ...
Brush +9 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Bioinspired Soft Machines: Engineering Nature’s Grace into Future Innovations
Journal of Functional BiomaterialsThis article explores the transformative advances in soft machines, where biology, materials science, and engineering have converged. We discuss the remarkable adaptability and versatility of soft machines, whose designs draw inspiration from nature’s ...
Ajay Vikram Singh +10 more
doaj +1 more source