Results 51 to 60 of about 1,189,370 (297)
Frontiers in Marine Science, 2021 The integrity of coral reefs has increasingly been threatened by human development and climate change. As a result, the concept of ecological resilience – an ecosystem's capability to resist and recover from environmental stressors – has become an ...
Ashley H. Y. Bang +10 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Survey on Centrality Metrics and Their Implications in Network Resilience
CoRR, 2020 Main paper: 36 pages, 2 figures.
Zelin Wan +4 more
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Review of Power System Resilience Concept, Assessment, and Enhancement Measures
Applied SciencesPower systems are generally designed to be reliable when faced with low-impact, high-probability, and expected power outages. By contrast, the probability of extreme event (extreme weather or natural disasters) occurrence is low, but may seriously affect
Jhih-Hao Lin, Yuan-Kang Wu
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Managing for local resilience: towards a strategic approach [PDF]
, 2013 The term resilience is increasingly being used to capture the challenges involved in managing in ‘hard times’. This article aims to provide one of the first empirical studies of the term’s application to local authority interventions around emergency ...
Shaw, Keith, Maythorne, Louise
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
IET Generation, Transmission & Distribution, 2021 The exponential increase in the frequency and intensity of high impact low probability weather‐related events have pivoted the paradigm of research pertaining to power systems towards resilience.
Abdullah Akram Bajwa +5 more
doaj +1 more source
The Effect of Time-Varying Value on Infrastructure Resilience Assessments
IEEE Access, 2021 Infrastructure resilience for a scenario can be assessed quantitatively from resilience curves that plot the evolution of system performance. Summary metrics map these curves to a single value to facilitate comparisons of different systems, scenarios ...
Craig R. Poulin, Michael B. Kane
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Cyber-Physical Resilience: Definition and Assessment Metric
IEEE Transactions on Smart Grid, 2019 Resilient operation of cyber-physical infrastructures in adversarial environments requires: 1) toughness: maintenance of core crucial sub-functionalities despite ongoing intrusions and 2) elasticity: recovery of the normal system operation in a timely manner.
Andrew Clark 0001, Saman A. Zonouz
openaire +2 more sources