Results 71 to 80 of about 1,189,370 (297)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Operational resilience metrics for power systems with penetration of renewable resources

open access: yesIET Generation, Transmission & Distribution, 2023
Modern power grid is evolving towards carbon neutrality by deploying increasing amount of renewable energy resources. However, the impact of renewable generation on power system planning and operation is not sufficiently investigated, especially the ...
Jianzhong Gui   +4 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Resilience: an all-encompassing solution to global problems? A biopolitical analysis of resilience in the policies of EC, FEMA, UNDP, USAID, WB, and WEF [PDF]

open access: yes, 2015
This thesis examines the use of resilience in international policy-making. A concept that originally meant an ability of ecosystems to absorb disturbance has not only been welcomed in many disciplines outside ecology, but lately become popular in the ...
Jakola, Iiris
core   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Resilience of road networks to natural hazards: A systematic literature review

open access: yesTransportation Engineering
Road networks are essential to societal functioning yet remain highly vulnerable to natural hazards and cascading disruptions. This study presents a systematic review of road network resilience, synthesizing resilience metrics, assessment methods, and ...
Yohannes Sisay Zeleke   +2 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Towards Reliable Resilience Metrics in Corporate Settings: Content Validity Considerations

open access: yesBusiness Systems Research
Firm resilience is a critical concept for organisations aiming to navigate disruptions effectively, yet its translation into regularly applicable metrics remains underdeveloped.
Schötz Enrico
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Resilient Systems : Metrics to Measure Resilience

open access: yes, 2022
As our society becomes more dependent on different types of software systems, it is vital that they operate normally under all types of stress. System resilience is a growing subject within computer science and the tech industry. Resilience can be defined as the persistence of dependability when facing change, for example against failures and attacks ...
openaire   +1 more source

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