Results 61 to 70 of about 214,113 (341)

A Comparison of Critical Infrastructure Resilience Quantification Techniques [PDF]

, 2017
Promoting the resilience of critical infrastructure, when subjected to different hazardous events, is vital. However, applying inappropriate and/or imprecise resilience metrics or quantification techniques could increase the costs of resilience ...
Hajializadeh, Donya, Imani, Maryam
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Review of Power System Resilience Concept, Assessment, and Enhancement Measures

Applied Sciences
Power systems are generally designed to be reliable when faced with low-impact, high-probability, and expected power outages. By contrast, the probability of extreme event (extreme weather or natural disasters) occurrence is low, but may seriously affect
Jhih-Hao Lin, Yuan-Kang Wu
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Operational resilience metrics for power systems with penetration of renewable resources

IET Generation, Transmission & Distribution, 2023
Modern power grid is evolving towards carbon neutrality by deploying increasing amount of renewable energy resources. However, the impact of renewable generation on power system planning and operation is not sufficiently investigated, especially the ...
Jianzhong Gui, Hangtian Lei, Timothy R. McJunkin, Bo Chen, Brian K. Johnson   +4 more
doaj   +1 more source

The Mental Health Ecosystem: Extending Symptom Networks With Risk and Protective Factors

Frontiers in Psychiatry, 2021
Inspired by modeling approaches from the ecosystems literature, in this paper, we expand the network approach to psychopathology with risk and protective factors to arrive at an integrated analysis of resilience.
Gabriela Lunansky, Claudia D. van Borkulo, Claudia D. van Borkulo, Jonas M. B. Haslbeck, Max A. van der Linden, Cristian J. Garay, Martín J. Etchevers, Denny Borsboom   +7 more
doaj   +1 more source

The Coherence Problem: Mapping the Theory and Delivery of Infrastructure Resilience Across Concept, Form, Function, and Experienced Value [PDF]

, 2015
In this contribution we explore the interface between the functional characteristics of infrastructures as artefacts and social need supplier. Specifically we are concerned with the ways in which infrastructure performance measures are articulated and ...
Jeffrey, P., Smith, H.
core  

Online Fault Classification in HPC Systems through Machine Learning

, 2019
As High-Performance Computing (HPC) systems strive towards the exascale goal, studies suggest that they will experience excessive failure rates. For this reason, detecting and classifying faults in HPC systems as they occur and initiating corrective ...
A Gainaru, Alessio Netti, C Engelmann, F Cappello, I Cohen, M Snir, O Tuncer, Z Lan   +7 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Impact of State Fiscal Policy on States\u27 Resilience Entering the Great Recession [PDF]

, 2019
The U.S. economy entered the Great Recession in December 2007 and exited in June 2009. This national statistic obscures a wealth of state-level data shedding light on the policies and conditions that helped some states withstand that recessionary shock ...
Paulson Gjerde, Kathy A., Prescott, Peter, Rice, Jennifer   +2 more
core   +1 more source