Results 191 to 200 of about 29,160 (257)

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Protocol for fixation and staining of postmortem human brain tissue optimized for focused ion beam-scanning electron microscopy. [PDF]

STAR Protoc
Maier MJ, Lewis DA, Freyberg Z, Glausier JR.   +3 more
europepmc   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source

Optimization of Prediction Model for Glass Transition Temperature of Thermoplastic Toughened Bismaleimide Resin. [PDF]

Polymers (Basel)
Zhang J, Luo Y, Li W, Yang H, Zhang Y, Zhou H, Zhong X, Bao J.   +7 more
europepmc   +1 more source

Mitigation of artifacts in imaging biosamples with optical scanning transmission electron microscopy. [PDF]

Appl Microsc
Kievits AJ, Duinkerken BHP, Lane R, Giepmans BNG, Hoogenboom JP.   +4 more
europepmc   +1 more source

Combining the CryoCapsule, HPM live µ and R221 conductive resin to track endosome from live imaging to electron microscopy using high-pressure freezing. [PDF]

Sci Rep
Heiligenstein X, Kodera C, Bret Y, Eyraud F, Heiligenstein J, Belle M.   +5 more
europepmc   +1 more source

In Vitro Shear Bond Strength of Additively Manufactured Denture Base Resins to Hard Chairside Reline Materials. [PDF]

Int Dent J
Yoo JH, Kim J, Park Y, Kim JH.
europepmc   +1 more source

SKOOTS: Skeleton-Oriented Object Segmentation for Mitochondria in High-Resolution Cochlear EM Datasets. [PDF]

Adv Sci (Weinh)
Buswinka CJ, Osgood RT, Nitta H, Indzhykulian AA.   +3 more
europepmc   +1 more source

On an Epoxy Resin Embedding Method for Ultra-thin Sectioning

Denshi kenbikyo, 1959
openaire   +1 more source

Integrated light and electron microscopy workflow for morphological, molecular and ultrastructural analysis of spheroids. [PDF]

PLoS One
Tratnjek L, Janev A, Resnik N, Cerkvenik U, Kreft ME.   +4 more
europepmc   +1 more source