Results 121 to 130 of about 1,998,168 (383)

Reappraisal of IgG subclass deficiencies: a retrospective comparative cohort study

open access: yesFrontiers in Immunology
ObjectiveThe aim of the present study was to investigate the clinical spectrum of IgG subclass deficiencies (IgGSDs) and assess the relative clinical significance of diagnosing each specific IgGSD disorder as compared to the common variable ...
Damla Dogru   +14 more
doaj   +1 more source

Committing to transparency to resist corruption [PDF]

open access: yes
This paper examines firms' incentives to commit to a transparent behavior (that precludes bribery) in a competitive procedure modeled as an asymmetric information beauty contest managed by a corrupt agent.
Ariane Lambert-Mogiliansky   +1 more
core  

Liquid Assets? Industry Raised The Bar to Resist Alcohol Taxes [PDF]

open access: yes, 2009
States coping with the budget woes often raise taxes to help cover shortfalls. Frequently, "sin taxes" are among the first to face a potential increase.
Peter Quist
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Who Gets to Resist?

open access: yesPolitikon
This paper examines contested definitions of terrorism and resistance, analyzing how the US and India instrumentalize such labels to suppress dissent and monopolize violence.
Mohammad Amaan Siddiqui
doaj   +1 more source

Effect of expiratory resistive loading on the noninvasive tension-time index in COPD [PDF]

open access: bronze, 2000
W. H. Thompson   +3 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Composite gaskets are compatible with liquid oxygen, resist compression set [PDF]

open access: yes, 1966
Gaskets fabricated by laminating fluorocarbon polymers with fiber glass cloth have a low compression set. Their flexibility is not subject to drastic changes at the temperature of liquid oxygen with which they are used.
Gosnell, R. B.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control

open access: yesFrontiers in Immunology
In atopic dermatitis (AD), lesional skin is frequently colonized by Staphylococcus aureus, which promotes clinical symptoms of the disease. The inflammatory milieu in the skin is characterized by a Th2 response, including M2 macrophages, which cannot ...
Christina Schmidt   +10 more
doaj   +1 more source

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