Results 101 to 110 of about 8,073,312 (304)

Early Gut Microbiota Intervention Suppresses DSS-Induced Inflammatory Responses by Deactivating TLR/NLR Signalling in Pigs

open access: yesScientific Reports, 2017
Recent metagenomic studies suggest that innate and adaptive immune phenotypes can be programmed via gut microbiota-host interactions mediated via activation of pattern recognition receptors (PRRs) on host cells.
Yi Xiao   +9 more
doaj   +1 more source

Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting

open access: yesBMC Medical Research Methodology, 2019
Background Antimalarial clinical efficacy studies for uncomplicated Plasmodium falciparum malaria frequently encounter situations in which molecular genotyping is unable to discriminate between parasitic recurrence, either new infection or recrudescence.
Prabin Dahal   +5 more
doaj   +1 more source

Microwave radiation induced magneto-oscillations in the longitudinal and transverse resistance of a two dimensional electron gas

open access: yes, 2003
We confirm the existance of magneto-resistance oscillations in a microwave-irradiated two-dimensional electron gas, first reported in a series of papers by Zhudov et al. and Mani et al.
A.S. Sachrajda   +17 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Equations to assess the impact resistance of fiber composites [PDF]

open access: yes, 1972
Numerical analysis of impact resistance of composite materials containing fibers is discussed. Mathematical model of longitudinal impact resistance is presented. Potential impact resistance of various fiber composites as obtained by numerical analysis is
Chamis, C. C.   +2 more
core   +1 more source

Current Driven tri-stable Resistance States in Magnetic Point Contacts

open access: yes, 2009
Point contacts between normal and ferromagnetic metals are investigated using magneto-resistance and transport spectroscopy measurements combined with micromagnetic simulations.
Balkashin, O. P.   +6 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Youth as change makers on antimicrobial resistance: an evidence-based call-to-action

open access: yesNature Communications
Youth represent un-tapped potential within the fight against antimicrobial resistance (AMR). This commentary describes the co-creation process of the Youth Manifesto on AMR which seeks to generate consensus on how equitable engagement of youth can be ...
Jessica Mitchell   +12 more
doaj   +1 more source

Identification of molecular markers associated to new sources of resistance to the root-knot nematode in cotton : S02T04 [PDF]

open access: yes, 2013
The root-knot nematode (RKN) Meloidogyne incognita is a major constraint in cotton (Gossypium hirsutum L.) production in numerous countries. Control of RKN has been hampered by the lack of options for crop rotation and even more, by the lack of high ...
Barroso, Paulo Augusto Vianna   +4 more
core  

Home - About - Disclaimer - Privacy