Results 281 to 290 of about 8,583,441 (292)

Turning Susceptibility into Strength: A New Era of Durable Resistance in Plants Through Genome Editing. [PDF]

Plants (Basel)
Thakur S, Kaur S, Adhikari S, Sabharwal P, Fu Y, Meru G.   +5 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

HIV Dolutegravir resistance and multiclass failure in Mozambique: findings from a real-world cohort. [PDF]

BMC Infect Dis
Ciccacci F, Doro Altan AM, Majid N, Orlando S, Uamusse E, Rafael M, Sidumo Z, Germano P, Guidotti G, Perno CF.   +9 more
europepmc   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Local therapy overcomes primary resistance to target-immunotherapy combination in unresectable hepatocellular carcinoma. [PDF]

Cancer Immunol Immunother
Chen X, Piao M, Zhou Z, Wang S, Li S, Zhang N, Sun B, Liu K, Yang X, Yang X, Shi X, Zhu C, Zhao H.   +12 more
europepmc   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Molecular characterization of drug-resistance genes and dynamics of multidrug-resistant Salmonella spp. in waterfowl: a pre- and post-antibiotic ban surveillance in Guangdong, China from 2013 to 2023. [PDF]

BMC Microbiol
Yang Z, Li W, Yu B, Liu M, Li R, Zhong J, Zhu W, Zhang Y, Chen J, Zhang J, Chen J.   +10 more
europepmc   +1 more source

Exploring drug resistance genes in <i>Acinetobacter baumannii</i> using metagenomic next-generation sequencing. [PDF]

Front Microbiol
Li G, Lao J, Jiang Y, Tang P, Huang H, He L, Yuan K, Lai X.   +7 more
europepmc   +1 more source

Phenotypic and genotypic characterization of probiotic strains in the context of antimicrobial resistance. [PDF]

Front Vet Sci
Kerek Á, Palkovicsné Pézsa N, Kaszab E, Jerzsele Á, Farkas O.   +4 more
europepmc   +1 more source

Genomic Loci for Sclerotinia Stem Rot Resistance and Chlorophyll Stability in <i>Brassica napus</i>: Integrating GWAS With Microbiome Insights. [PDF]

Plant Environ Interact
Chawade A, Thuraga V, Sepp SS, Ghosh S, Ghadamgahi F, Odilbekov F, Muthusamy S, Vetukuri RR, Abreha KB.   +8 more
europepmc   +1 more source