Results 91 to 100 of about 4,242,053 (289)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Flexible Pedagogy, Flexible Practice: Notes from the Trenches of Distance Education [PDF]

open access: yes, 2011
Flexibility has become a watchword in modern education, but its implementation is by no means a straightforward matter. Flexible Pedagogy, Flexible Practice sheds light on the often taken-for-granted assumptions that inform daily practice and examines ...
Elizabeth Burge   +2 more
core  

Distance software: design and analysis of distance sampling surveys for estimating population size [PDF]

open access: yes, 2009
1. Distance sampling is a widely used technique for estimating the size or density of biological populations. Many distance sampling designs and most analyses use the software Distance. 2.
Hedley, S L   +27 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Management of Distance Education: Held 24-28 June, 1996 Barbados: Collection of Selected Handouts

open access: yes, 1996
This workshop item forms the first of a series of three presented jointly by the University of the West Indies and the International Extension College.
The Distance Education Center of the University of the West Indies and The International Extension College Training Link
core  

The influence of distance between the floats of catamaran hull

open access: yesAnnals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2019
This study presents the influence of the distance between the floats of catamaran for ship calm water resistance. As we know, a catamaran is composed by 2 floats, each float having its own wave systems in calm water.
Alin Pohilca   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The preliminary successes and drawbacks of a turn to distance design studio learning.

open access: yes, 2020
It seems the technological campuses of tomorrow have manifested today as an essential and spontaneous response to the COVID-19 world outbreak. This article briefly discusses the current pivot from an on-campus physical design studio curriculum towards a ...
Marshalsey, Lorraine
core  

Developing a conceptual framework for planning distributed education within Alberta’s comprehensive community institutions [PDF]

open access: yes, 2018
Previous research has revealed challenges faced by post-secondary institutions (PSIs) seeking to add or expand distributed education options within institutional contexts originally developed to support more traditional, face-to-face classroom learning.
Wilde, Russell
core  

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