Results 101 to 110 of about 7,571,911 (312)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Migration of the rice blast fungus, Magnaporthe grisea [PDF]
, 2007 The diversity and structure of populations of Magnaporthe grisea, the main fungal pathogen of rice, was described in many countries during the last 20 years. The expected clonal structure of the populations has been illustrated in many studies.
Andriantsimialona, Dodelys +6 more
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Bounds for resistance-distance spectral radius
, 2013 Lower and upper bounds as well as Nordhause-Gaddum-type results for the resistance-distance spectral radius are obtained.
Maden, A. Dilek Gungor +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The influence of distance between the floats of catamaran hull
Annals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2019 This study presents the influence of the distance between the floats of catamaran for ship calm water resistance. As we know, a catamaran is composed by 2 floats, each float having its own wave systems in calm water.
Alin Pohilca +3 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Resistance Distance and Kirchhoff Index of $Q$ -Double Join Graphs
IEEE Access, 2019 Let $Q(G)$ be the graph derived from $G$ by inserting a new vertex into every edge of $G$ and by connecting edges of these new vertices that are on adjacent edges of $G$ , and $Q$ -double join of $G$ , $G_{1}$ and $G_{2}$ denoted by $G^{Q ...
Weizhong Wang, Tingyan Ma, Jia-bao Liu
semanticscholar +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source