Results 111 to 120 of about 1,259,159 (318)

Resistance to leaf rust in cultivars and wheat lines from Paraguay

Agrociencia Uruguay
Leaf rust (LR) of bread wheat (Triticum aestivum L.), caused by the fungus Puccinia triticina Eriks, is one of the most important diseases in Paraguay, the Southern Cone of America and worldwide.
Ruth Scholz, Silvia Pereyra, Paula Silva, Silvia Germán   +3 more
doaj   +1 more source

Molecular analysis of resistance genes against phylloxera, antracnosis and crown gall disease in a collection of different grapevine accessions

Laimburg Journal, 2019
In the year 2012 the Laimburg Research Centre, in collaboration with the Autonomous Province of Bolzano and the private platform InnoVitis in Marlengo, has started a project called RebSelect with the aim to characterise a collection of about 150 ...
Margot Raffeiner, Elena Zini, Thomas Letschka   +2 more
doaj   +1 more source

Diversity analysis of Streptomycetes and associated phosphotranspherase genes in soil [PDF]

, 2012
An attempt was made to verify the observation that Streptomyces griseus was prevalent in soil based on isolation work. A genus-specific PCR was developed for Streptomyces based on the housekeeping gene atpD and used to investigate species diversity ...
Paris Laskaris, Takuya Sekine, Laskaris Paris, Sekine Takuya, Elizabeth M H Wellington, Sekine, Takuya, Wellington, E. M. H., Laskaris, Paris, Wellington Elizabeth M. H.   +8 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

ZymoSoups: A High-Throughput Forward Genetics Method for Rapid Identification of Virulence Genes in Zymoseptoria tritici

Molecular Plant-Microbe Interactions
Septoria tritici blotch is caused by the fungus Zymoseptoria tritici and poses a major threat to wheat productivity. There are over 20 mapped loci in wheat that confer strong (gene-for-gene) resistance against this pathogen, but the corresponding genes ...
Haider Ali, Megan C. McDonald, Graeme J. Kettles   +2 more
doaj   +1 more source

Efficacy and mapping of resistance to Mycosphaerella graminicola in wheat

, 2011
Wheat is the most important food and feed crop, contributing about 19% of the required human dietary energy. The annual growth rate of the global cereal production -including wheat- is below one per cent.
Tabib Ghaffary, M.S.
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Multiplex Real-Time Polymerase Chain Reaction and Recombinase Polymerase Amplification: Methods for Quick and Cost-Effective Detection of Vancomycin-Resistant Enterococci (VRE)

Antibiotics
Background/Objectives: Vancomycin-resistant enterococci (VRE) are one of the leading causes of antibiotic-resistant infections in the hospital setting worldwide, and this has become a major issue, because most patients infected with this strain are ...
Ibukun Elizabeth Osadare, Abdinasir Abdilahi, Martin Reinicke, Celia Diezel, Maximilian Collatz, Annett Reissig, Stefan Monecke, Ralf Ehricht   +7 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs. [PDF]

, 2007
Parasite drug resistance is partly conferred by single-nucleotide polymorphisms (SNPs), and monitoring them has been proposed as an alternative to monitoring drug resistance.
Regös, Attila, Beck, Hans-Peter, Puijalon, Odile, Huber, E., Crameri, A., Regos, A., Crameri, Andreas, Mugittu, K., Felger, Ingrid, Sismeiro, Odile, Laubscher, Daniel, Marfurt, J., Genton, B., Laubscher, D., Puijalon, O., Felger, I., Burki, Richard, Beck, H. P., Coppee, Jean Yves, Genton, Blaise, Maire, N., Coppee, J. Y., Marfurt, Jutta, Mugittu, Kefas, Maire, Nicolas, Burki, R., Huber, Eric, Sismeiro, O.   +27 more
core   +1 more source