Results 101 to 110 of about 1,259,159 (318)

Antibiotic resistance gene abundances correlate with metal and geochemical conditions in Scottish soils [PDF]

, 2011
The vast majority of antibiotic resistant genes (ARG) acquired by human pathogens have originated from the natural environment. Therefore, understanding factors that influence intrinsic levels of ARG in the environment could be epidemiologically ...
Brajesh K Singh, Seánı́n M. Mccluskey, Seánín M. McCluskey, Colin D Campbell, David W. Graham, Charles W. Knapp, Hudson, Gordon, Charles W Knapp, Gordon Hudson, David W Graham, Seánín M McCluskey, McCluskey, Seánín M., Campbell, Colin D., Graham, David W., Knapp, Charles W., Singh, Brajesh K., Brajesh K. Singh, Colin D. Campbell   +17 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genome-Wide Association Analysis of Cowpea Mild Mottle Virus Resistance in Soybean Germplasms from Northeast China

Agronomy
Cowpea mild mottle virus (CpMMV) is an important viral pathogen that seriously influences the yield and seed quality of soybeans worldwide. Resistance breeding is one of the most effective, economical, and environmentally safe strategies for controlling ...
Yameng Luan, Siqi Yang, Yuting Wang, Yu Zhao, Xiaoyun Wu, Qingshan Chen, Zhaoming Qi, Xiaoxia Wu, Weiqin Ji, Xiaofei Cheng   +9 more
doaj   +1 more source

Detection and characterisation of genes encoding antibiotic resistance in the cultivable oral microflora.

, 2006
The emergence of antibiotic-resistant bacteria has become a major threat to public health. The increased use of antibiotics has selected for the dissemination of antibiotic resistance genes between organisms from different species and different genera ...
Villedieu, A., Villedieu, Aurelie
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Potato R1 resistance gene confers resistance against Phytophthora infestans in transgenic tomato plants

, 2010
Tomato is challenged by several pathogens which cause loss of production. One such pathogen is the oomycete Phytophthora infestans which is able to attack all the aerial parts of the plant.
Luigi Faino, ERCOLANO, MARIA RAFFAELLA, Testa, A., Maria Raffaella Ercolano, Paola Carli, Carli, P., Luigi Frusciante, FAINO, LUIGI, CRISTINZIO, GENNARO, Cristinzio, G., TESTA, ANTONINO, Gennaro Cristinzio, Ercolano, M.R., Antonino Testa, Faino, L., Frusciante, L., FRUSCIANTE, LUIGI, CARLI, PAOLA   +17 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

CCoAOMT positively regulates the biosynthesis of secondary metabolites in Zanthoxylum armatum

Frontiers in Agronomy
IntroductionThe rust disease caused by the fungus Coleosporium zanthoxyli in Zanthoxylum armatum leads to significant leaf damage. However, the genetic regulatory mechanisms underlying disease resistance in this plant remain unclear.MethodsThrough ...
Xiu Xu, Yingxia Hu, Yingming Lai, Tianhui Zhu, Tianhui Zhu, Tianhui Zhu, Shujiang Li, Shujiang Li, Shujiang Li, Yinggao Liu, Shuying Li, Chunlin Yang, Shan Han, Shan Han, Shan Han   +14 more
doaj   +1 more source

Immunological basis of differences in disease resistance in the chicken

, 2002
Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Rebel, J.M.J., Zekarias, B., Huurne, A.A.H.M., ter, Landman, W.J.M., Gruys, E., Pol, J.M.A.   +5 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source