Results 111 to 120 of about 3,772,305 (302)

Job Insecurity and Intention to Quit: The Role of Psychological Distress and Resistance to Change in the UAE Hotel Industry. [PDF]

Int J Environ Res Public Health, 2022
Baquero A.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Do teachers' educational philosophies affect their digital literacy? The mediating effect of resistance to change. [PDF]

Educ Inf Technol (Dordr), 2022
Alanoglu M, Aslan S, Karabatak S.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Therapeutic Efficacy of Sulfadoxine-Pyrimethamine and Prevalence of Resistance Markers in Tanzania Prior to Revision of Malaria Treatment Policy: Plasmodium Falciparum Dihydrofolate Reductase and Dihydropteroate Synthase Mutations in Monitoring in Vivo Resistance. [PDF]

, 2004
Prior to the 2001 malarial treatment policy change in Tanzania, we conducted trials to assess the efficacy of sulfadoxine-pyrimethamine (SP) and the usefulness of molecular markers in monitoring resistance.
Abdulla, Salim, Beck, Hans-Peter, Kataraihya, Johannes, Lemnge, Martha, Malisa, Allen, Mshinda, Hassan, Mugittu, Kefas, Mwita, Alex, Ndejembi, Modesta, Nkya, Watoky, Premji, Zulfikar   +10 more
core   +1 more source

Resistance to Change as a Mediator Between Conscientiousness and Teachers' Job Satisfaction. The Moderating Role of Learning Goals Orientation. [PDF]

Front Psychol, 2021
Paloş R, Vîrgă D, Craşovan M.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stimulation of Organizational Inertia: Identification of the Dimensions and Components of Organizational Inertia at Mazandaran University of Medical Sciences, Iran

Journal of Medical Education Development, 2020
Background & Objective: Considering the current unstable environment, organizations are faced with numerous changes and should adapt to various environmental factors.
Kosar Momeni Badeleh, Taraneh Enayati
doaj  

The impact of implementing a person-centred pain management intervention on resistance to change and organizational culture. [PDF]

BMC Health Serv Res, 2021
Angelini E, Wolf A, Wijk H, Brisby H, Baranto A.   +4 more
europepmc   +1 more source