Results 161 to 170 of about 1,503,887 (312)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Resistance to Technological Change in Academia

Current Issues in Education, 2015
Initiating changes in technology, promoting utilization, and managing resistance by faculty may be among the most pressing challenges for academic leadership.
Linda Moerschell
doaj  

Resistance to change: AMR gene dynamics on a commercial pig farm with high antimicrobial usage. [PDF]

Sci Rep, 2020
Pollock J, Muwonge A, Hutchings MR, Mainda G, Bronsvoort BM, Gally DL, Corbishley A.   +6 more
europepmc   +1 more source

Successfully Leading Needed Organization Change: Strategies for Leading Change and Managing Resistance

, 2013
Organizations are continually undergoing changes to make improvements to business strategies, to remain competitive, and to become efficient and effective. Change is an inevitable part of an organization.
DeVose, C.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Artificial intelligence anxiety among nursing and midwifery students: the role of resistance to change - a cross-sectional study. [PDF]

BMC Med Educ
Güner Ö, Aydın MS.
europepmc   +1 more source

Technology anxiety and resistance to change behavioral study of a wearable cardiac warming system using an extended TAM for older adults. [PDF]

PLoS One, 2020
Tsai TH, Lin WY, Chang YS, Chang PC, Lee MY.   +4 more
europepmc   +1 more source

Project managers beware : the resistance to change you experience may be due to Senior Leadership rather than just your methods or employees

, 2014
For many years Organisations implementing change Projects have noticed that their projects often fail or have sub-optimal results. The first academics to study this field (Lewin 1945) believed that the issue was solely caused by the method and sequence ...
Donald, Mathew (S30765)
core