Results 241 to 250 of about 2,503,389 (311)

Epigenetic regulation of cancer stem cell plasticity and relapse competence in EGFR-mutant lung cancer. [PDF]

Front Oncol
Sun X, Xu S, Guo Q.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Azithromycin Derivatives for Overcoming Antibacterial Resistance: Structural Modification and Structure-Activity Relationships. [PDF]

Int J Mol Sci
Ngece K, Paca AM, Buwa-Komoreng LV, Aderibigbe BA, Khwaza V.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Clinical correlates for fluconazole resistance in <i>Candida</i> bloodstream infections. [PDF]

Front Public Health
Li Z, Wang T, Zhang M, Cao S, Liu B, Fan C, Lin G, Ming Y.   +7 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Outcomes of a modified intralesional bleomycin technique for recalcitrant warts: A case series

JAAD Case Reports
Hasan Ashkanani, MD, Mattia Mattarocci, MD, Abdulaziz Alrasheed, MBBS, Wael Al-Daraji, MD, MRCP   +3 more
doaj   +1 more source

Correction to "Chidamide (a Histone Deacetylase Inhibitor) Plus Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC): A Phase Ib Trial". [PDF]

MedComm (2020)
europepmc   +1 more source

Acquired TRAIL Resistance Promotes Cancer Stemness and Malignant Behavior through CD44-SPHK1-STAT3 Signaling in Colorectal Cancer. [PDF]

Biomol Ther (Seoul)
Kim SL, Jin BC, Seo SY, Kim SW.
europepmc   +1 more source