Results 281 to 290 of about 3,559,343 (361)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Outcomes of a modified intralesional bleomycin technique for recalcitrant warts: A case series

JAAD Case Reports
Hasan Ashkanani, MD, Mattia Mattarocci, MD, Abdulaziz Alrasheed, MBBS, Wael Al-Daraji, MD, MRCP   +3 more
doaj   +1 more source

Understanding multi-azole resistance in <i>Aspergillus fumigatus</i>: the impact of non-<i>cyp51A</i> mutation and efflux pump overexpression. [PDF]

Front Fungal Biol
Sen P, Kumar L, Shankar J, Vijayaraghavan P.   +3 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

High-resolution characterization of the temporal and spatial distribution of antimicrobial resistance in Escherichia coli from pigs. [PDF]

J Antimicrob Chemother
Abraham S, Lee ZZ, Jordan D, Stegger M, Saidenberg ABS, Lugsomya K, Lee T, Mukerji S, Price L, Nairn K, Abraham RJ.   +10 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Antiviral Resistance in Influenza: Clinical and Public Health Implications. [PDF]

Influenza Other Respir Viruses
Ngiam JN, Koh MCY, Hayden FG.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Bacterial, Antimicrobial, and Clinical Profile of Multidrug-Resistant Gram-Negative Bacilli Isolates From Intensive Care Unit Patients. [PDF]

Cureus
Chavan VG, Pawar S, Patil S.
europepmc   +1 more source