Results 91 to 100 of about 7,235 (313)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Das Terras de Benvirá: resistence and surrender in Geraldo Vandré’s carrer (1964-1973)
This paper had the aim of analyzing thoughout the study of Geraldo Vandre’s discography in a period between his first Long Play in 1964 until the last in 1973 the aesthetic-ideological componentes of the album Das Terras de Benvirá that offering many ...
Paula, Rai Araujo de
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Functional System of Lysozyme and Anti-Lysozyme in Plague Agent and Flea Organism Interralations
Lysozyme is shown to be one of the factors of flea`s natural non-specific resistence. Lysozyme is detected in various species of rodents fleas. Besides, some plague agent strains are shown to possess anti-lysozyme activity.
N.V. Sakhno
doaj +1 more source
Polimorfisme Gen Natural Resistence Associated Macrophage Protein-1 (NRAMP-1) Dengan PCR-RFLP dari Ekstrak Saliva Menggunakan Enzim Restriksi Fok 1 [PDF]
Several study has been reported that Polymorphism Gen Natural Resistence Associated Macrophage Protein-1 (NRAMP-1) with PCR-RFLP from extract saliva used restriction Fok 1 enzyme.
Toding Buak, Meyanti
core
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
La thèse a pour but de définir le concept de résistance esthétique et d’en décrire les repercussions dans la production musicale expérimentale du Xxe siècle. Le potentiel politique de résistance inhérent à la nature des avant-garde est susceptible d’etre
D'Aversa, Anna Sara
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Produção e avaliação do uso de pozolana com baixo teor de carbono obtida da cinza de casca de arroz residual para concreto de alto desempenho [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.Os benefícios da utilização da cinza de casca de arroz como adição pozolânica em argamassas e concretos têm sido amplamente ...
Santos, Silvia
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

