Results 91 to 100 of about 7,235 (313)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Das Terras de Benvirá: resistence and surrender in Geraldo Vandré’s carrer (1964-1973)

open access: yes, 2021
This paper had the aim of analyzing thoughout the study of Geraldo Vandre’s discography in a period between his first Long Play in 1964 until the last in 1973 the aesthetic-ideological componentes of the album Das Terras de Benvirá that offering many ...
Paula, Rai Araujo de
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Functional System of Lysozyme and Anti-Lysozyme in Plague Agent and Flea Organism Interralations

open access: yesПроблемы особо опасных инфекций, 2009
Lysozyme is shown to be one of the factors of flea`s natural non-specific resistence. Lysozyme is detected in various species of rodents fleas. Besides, some plague agent strains are shown to possess anti-lysozyme activity.
N.V. Sakhno
doaj   +1 more source

Polimorfisme Gen Natural Resistence Associated Macrophage Protein-1 (NRAMP-1) Dengan PCR-RFLP dari Ekstrak Saliva Menggunakan Enzim Restriksi Fok 1 [PDF]

open access: yes, 2014
Several study has been reported that Polymorphism Gen Natural Resistence Associated Macrophage Protein-1 (NRAMP-1) with PCR-RFLP from extract saliva used restriction Fok 1 enzyme.
Toding Buak, Meyanti
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Phenomenology of aesthetics resistence in 20th century music : new avant-gardes and deviations of the notion of resistence in contemporary musics

open access: yes, 2018
La thèse a pour but de définir le concept de résistance esthétique et d’en décrire les repercussions dans la production musicale expérimentale du Xxe siècle. Le potentiel politique de résistance inhérent à la nature des avant-garde est susceptible d’etre
D'Aversa, Anna Sara
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Produção e avaliação do uso de pozolana com baixo teor de carbono obtida da cinza de casca de arroz residual para concreto de alto desempenho [PDF]

open access: yes, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.Os benefícios da utilização da cinza de casca de arroz como adição pozolânica em argamassas e concretos têm sido amplamente ...
Santos, Silvia
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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