Results 61 to 70 of about 33,766 (287)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

“A minor is required for small home services”: child and youth labor in the carioca domestic service (1880-1930)

open access: yesRevista Mundos do Trabalho, 2019
It is opportune in the present article to emphasize the presence of other important social agents in the composition of domestic service – the labor of children and youth.
Natália Batista Peçanha
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Konflik Internal Multikulturalisme dalam Film Good Bye Lennin!

open access: yesParadigma: Jurnal Kajian Budaya, 2015
Germany is one of several countries in the world that has ever been upside-down in historical experience. A long history proved that Germany was used to be a union. But unfortunately it had split based on ideological differences.
Resti Nurfaidah
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Evaluation of resistance to natural poisoning by Amorimia septentrionalis in goats which had received sodium monofluoroacetate degrading bacteria

open access: yesPesquisa Veterinária Brasileira
: Amorimia septentrionalis is an important sodium monofluoroacetate (MFA) containing plant that causes sudden death in ruminants in northeastern Brazil. MFA degrading bacteria are being used in the prevention against poisoning by this plant.
Danielle A.N. Pessoa   +7 more
doaj   +1 more source

L’attentato di Ceretolo [PDF]

open access: yesDiacronie. Studi di Storia Contemporanea, 2014
This paper aims to analyze the role and the pattern of the militant lawyering of Leonida Casali, one of the leading members of Bologna section of the Italian Communist Party and of the Democratic Solidarity Committee during the postwar period.
Nicola Caroli
doaj  

Resistance in Vancomycin-Resistant Enterococci

open access: yesInfectious Disease Clinics of North America, 2020
Serious infections owing to vancomycin-resistant enterococci have historically proven to be difficult clinical cases, requiring combination therapy and management of treatment-related toxicity. Despite the introduction of new antibiotics with activity against vancomycin-resistant enterococci to the therapeutic armamentarium, significant challenges ...
William R, Miller   +3 more
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Posible aislamiento clínico de Staphylococcus cohnii resistente a vancomicina Posible clinical isolate of Staphylococcus cohnii resistant to vancomicyn

open access: yesInfectio, 2006
Staphylococcus cohnii se encuentra comúnmente en la piel y el tracto gastrointestinal de personas sanas y, ocasionalmente, puede causar infecciones hospitalarias y en la comunidad.
PEDRO MARTÍNEZ, SALIM MÁTTAR
doaj  

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