Results 61 to 70 of about 2,873 (264)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Contribuições de Viktor Emil Frankl ao conceito de resiliência
Estudos de Psicologia (Campinas)Trata-se de um estudo sobre resiliência-capacidade do ser humano de enfrentar, sobrepor-se e ser fortalecido por experiências de adversidade que tem por objetivo discuti-la de acordo com a visão de Viktor Emil Frankl: a logoteoria.
Daniel Rocha Silveira, Miguel Mahfoud
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شخصية الأمير عبد القادر من منظور الآخر. ترجمة كتاب عبد القادر لقوستاف دوقا أنموذجا
إنسانيات, 2003 Thanks to his great mastery of military strategy, his skill as statesman, his national heroism in the Algerian resistance, and also to this deep thinking on intellectual questions, and his poetic output, Emir Abdelkader was able to go beyond the borders ...
عبد القادر شرشار
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UNICONE PLUS VS. UNICONE - IN VITRO CYCLIC FATIGUE STUDY AT DIFFERENT ENVIROMENTAL TEMPERATURES
Česká Stomatologie a Praktické Zubní Lékařství, 2020 Introduction, aim: The issue of fracture of endodontic nickel-titanium instruments is quite extensive. It is an alloy that has the ability to change its internal structure.
A. Jusku +5 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Resisting Bacterial Drug Resistance [PDF]
Chemistry & Biology, 2003 In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Reflextions on itinerant education on EJA: report of a specialist teacher
Revista Educação Especial, 2010 This paper has the objective to analyse and reflect on the performance of the itinerant teacher who works with students with intellectual disabilities at Education of young and adults.
Annie Gomes Redig
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Resistance and cross‐resistance to abacavir [PDF]
HIV Medicine, 2001 Background Abacavir (ABC) is a potent nucleoside reverse transcriptase inhibitor (NRTI) used in multi‐drug antiretroviral regimens and in combination with other NRTIs, protease and/or non‐nucleoside reverse transcriptase inhibitors (NNRTIs) in both treatment naive and treatment experienced patients.Patterns of resistance Resistance to ABC has been ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source