Results 11 to 20 of about 176,204 (272)

A whole‐cell hypersensitive biosensor for beta‐lactams based on the AmpR‐AmpC regulatory circuit from the Antarctic Pseudomonas sp. IB20

Microbial Biotechnology
Detecting antibiotic residues is vital to minimize their impact. Yet, existing methods are complex and costly. Biosensors offer an alternative. While many biosensors detect various antibiotics, specific ones for beta‐lactams are lacking.
Sebastián Higuera‐Llantén, Manuel Alcalde‐Rico, Felipe Vasquez‐Ponce, Claudia Ibacache‐Quiroga, Jesús Blazquez, Jorge Olivares‐Pacheco   +5 more
doaj   +2 more sources

Evaluation of Allplex™ Entero-DR assay for detection of antimicrobial resistance determinants from bacterial cultures

BMC Research Notes, 2020
Objective To evaluate the sensitivity and specificity of the Allplex™ Entero-DR, a quantitative PCR-based method, for the detection of β-lactamase-encoding genes and vancomycin-resistance determinants in 156 previously characterized Gram-negative bacilli
María Fernanda Mojica, Elsa De La Cadena, Adriana Correa, Tobias Manuel Appel, Christian José Pallares, María Virginia Villegas   +5 more
doaj   +1 more source

Genomic Analysis of CTX-M-Group-1-Producing Extraintestinal Pathogenic E. coli (ExPEc) from Patients with Urinary Tract Infections (UTI) from Colombia

Antibiotics, 2020
Background: The dissemination of the uropathogenic O25b-ST131 Escherichia coli clone constitutes a threat to public health. We aimed to determine the circulation of E.
Elsa De La Cadena, María Fernanda Mojica, Nathaly Castillo, Adriana Correa, Tobias Manuel Appel, Juan Carlos García-Betancur, Christian José Pallares, María Virginia Villegas   +7 more
doaj   +1 more source

Antimicrobial stewardship programs in seven Latin American countries: facing the challenges

BMC Infectious Diseases, 2023
Background Studies have shown that more than 50% of the antibiotics used in hospitals are unnecessary or inappropriate and, that antimicrobial resistance may cost up to 20 billion USD in excess medical costs each year.
Christian José Pallares, Jessica Porras, Elsa De La Cadena, Juan Carlos García-Betancur, Natalia Restrepo-Arbeláez, Sara María Cobo Viveros, Wanda Cornistein, Paulo Castañeda-Méndez, Luis Cuellar, Diogo Boldim-Ferreira, Jorge Chaverri-Murillo, Jaime A. Labarca, María Virginia Villegas   +12 more
doaj   +1 more source

In vitro antimicrobial activity of Bixa orellana L. leaves extract against anaerobic bacteria  associated to bacterial vaginosis and Lactobacillus spp.

Revista Peruana de Medicina Experimental y Salud Pública, 2022
Objective. To describe the in vitro antimicrobial activity of the methanolic extract of Bixa orellana L. leaves against anaerobic bacteria associated to bacterial vaginosis and  Lactobacillus spp. Materials and methods.
Jenny Marcas, Liz Romero, Oswaldo Tipiani, Steev Loyola, Jesús Tamariz   +4 more
doaj   +1 more source

Genome sequence of a virulent and hypermucoviscous-like Klebsiella michiganensis clinical isolate

BMC Research Notes, 2023
Objectives The hypermucoviscous-like phenotype has been described in Klebsiella pneumoniae species complex (KpSC) and was described as a contributor of increased virulence.
Alejandro Alvarado-Delgado, Nadia Rodríguez-Medina, Alejandro Sánchez-Pérez, Elsa María Tamayo-Legorreta, Jackeline Cerón-Lopez, Rayo Morfin-Otero, Ulises Garza-Ramos   +6 more
doaj   +1 more source

Comparative In Vitro Activity of Ceftolozane/Tazobactam against Clinical Isolates of Pseudomonas aeruginosa and Enterobacterales from Five Latin American Countries

Antibiotics, 2022
Background: Ceftolozane/tazobactam (C/T) is a combination of an antipseudomonal oxyiminoaminothiazolyl cephalosporin with potent in vitro activity against Pseudomonas aeruginosa and tazobactam, a known β-lactamase inhibitor.
Juan Carlos García-Betancur, Elsa De La Cadena, María F. Mojica, Cristhian Hernández-Gómez, Adriana Correa, Marcela A. Radice, Paulo Castañeda-Méndez, Diego A. Jaime-Villalon, Ana C. Gales, José M. Munita, María Virginia Villegas   +10 more
doaj   +1 more source

Resistencia antimicrobiana, una pandemia silenciosa

Salud Militar, 2023
Introducción: la resistencia a los antimicrobianos ha sido una problemática creciente a nivel global, la problemática afecta no solo la salud de personas, animales y el ambiente en general, sino que ha generado impactos de índole productivo y comercial. Una de las estrategias para abordar esta problemática es el enfoque de una salud.
Silvia Simon, Martín Labandera
openaire   +1 more source

Identification of mcr-1 Genes and Characterization of Resistance Mechanisms to Colistin in Escherichia coli Isolates from Colombian Hospitals

Antibiotics, 2023
We report the presence of the mcr-1 gene among 880 Escherichia coli clinical isolates collected in 13 hospitals from 12 Colombian cities between 2016 and 2019. Seven (0.8%) isolates were colistin resistant (MIC ≥ 4 µg/mL).
Elsa De La Cadena, Mateo Mahecha, Ana María Velandia, Juan Carlos García-Betancur, Laura J. Rojas, Jessica Porras, Christian Pallares, María Virginia Villegas   +7 more
doaj   +1 more source

Global resilience and new strategies needed for antimicrobial stewardship during the COVID‐19 pandemic and beyond

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 5, Issue 7, Page 707-715, July 2022., 2022
Abstract Resilience is having the ability to respond to adversity proactively and resourcefully. The coronavirus disease 2019 (COVID‐19) pandemic's profound impact on antimicrobial stewardship programs (ASP) requires clinicians to call on their own resilience to manage the demands of the pandemic and the disruption of ASP activities.
Debra A. Goff, Timothy P. Gauthier, Bradley J. Langford, Pavel Prusakov, Michael Ubaka Chukwuemka, Benedict C. Nwomeh, Khalid A. Yunis, Therese Saad, Dena van den Bergh, Maria Virginia Villegas, Nela Martinez, Andrew Morris, Diane Ashiru‐Oredope, Philip Howard, Pablo J. Sanchez   +14 more
wiley   +1 more source