Mechanism of inhibitory effect of atorvastatin on resistin expression induced by tumor necrosis factor-α in macrophages [PDF]
Journal of Biomedical Science, 2009 Atorvastatin has been shown to reduce resistin expression in macrophages after pro-inflammatory stimulation. However, the mechanism of reducing resistin expression by atorvastatin is not known. Therefore, we sought to investigate the molecular mechanisms
Chua Su-Kiat +3 more
doaj +3 more sources
Major Traumatic and Severe Thermal Injuries Lead to Immediate and Persistent Elevations in Circulating Concentrations of Resistin That Are Associated with Poor Clinical Outcomes and Impaired Innate Immune Responses [PDF]
BiomoleculesMajor trauma induces innate immune suppression, yet the underlying mechanisms are poorly understood. Resistin is an immunosuppressive molecule that is systemically elevated post-injury.
Emily Horner +14 more
doaj +2 more sources
Resistin as Modulator of Functional Activity of Phagocytes in Colostrum and Blood of Overweight and Obese Mothers [PDF]
BiomedicinesBackground/Objectives: Resistin is an adipokine involved in obesity pathogenesis, but its effects on blood and colostrum immune cells from obese mothers remain unclear.
Carla Roberta Silva Souza Antônio +9 more
doaj +2 more sources
Association between Resistin Levels and All-Cause and Cardiovascular Mortality: A New Study and a Systematic Review and Meta-Analysis. [PDF]
, 2015 CONTEXT: Studies concerning the association between circulating resistin and mortality risk have reported, so far, conflicting results. OBJECTIVE: To investigate the association between resistin and both all-cause and cardiovascular (CV) mortality risk ...
Copetti, M +10 more
core +21 more sources
Frontiers in Immunology, 2021 BackgroundResistin is an endogenous ligand of Toll-like receptor 4 that activates several inflammatory signals. But the physiological function of resistin in community-acquired pneumonia (CAP) remains unknown. The goal of this research was to explore the
Chun-Mei Feng +7 more
doaj +1 more source
Resistin Contribution to Cardiovascular Risk in Chronic Kidney Disease Male Patients
Cells, 2023 Background: Resistin is a molecule that belongs to the Resistin-Like Molecules family (RELMs), the group of proteins taking part in inflammatory processes. Increased resistin concentrations are observed in cardiovascular complications.
Katarzyna Romejko +5 more
doaj +1 more source
Resistin production from adipose tissue is decreased in db/db obese mice, and is reversed by rosiglitazone. [PDF]
PLoS ONE, 2013 OBJECTIVE: This study was designed to (1) investigate the expression profiles of resistin in db/db mice and its dynamic association with metabolic parameters; and (2) evaluate the effects of Rosiglitazone on production of resistin.
Hongying Ye +3 more
doaj +1 more source
Resistin increases monolayer permeability of human coronary artery endothelial cells. [PDF]
PLoS ONE, 2013 Resistin has been linked to obesity, insulin resistance, atherosclerosis, and the development of cardiovascular disease. Nevertheless, the effects and the molecular mechanisms of resistin on endothelial permeability, a key event in the development of ...
Md Saha Jamaluddin +5 more
doaj +1 more source
Frontiers in Nutrition, 2022 BackgroundSarcopenia is common in patients with chronic obstructive pulmonary disease (COPD) and is mainly caused by systemic inflammation. Resistin acts as a proinflammatory cytokine and is involved in the activation of multiple inflammatory signaling ...
Jinghan Gao +13 more
doaj +1 more source
Resistin production does not affect outcomes in a mouse model of acute surgical sepsis
PLoS ONE, 2022 Introduction Because of the strong correlation between the blood concentration of circulating resistin and the illness severity of septic patients, resistin has been proposed as a mediator of sepsis pathophysiology.
Anthony S. Bonavia +3 more
doaj +2 more sources