Resistin in Rodents and Humans [PDF]
Diabetes & Metabolism Journal, 2013 Obesity is characterized by excess accumulation of lipids in adipose tissue and other organs, and chronic inflammation associated with insulin resistance and an increased risk of type 2 diabetes.
Hyeong Kyu Park, Rexford S. Ahima
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Major Traumatic and Severe Thermal Injuries Lead to Immediate and Persistent Elevations in Circulating Concentrations of Resistin That Are Associated with Poor Clinical Outcomes and Impaired Innate Immune Responses [PDF]
BiomoleculesMajor trauma induces innate immune suppression, yet the underlying mechanisms are poorly understood. Resistin is an immunosuppressive molecule that is systemically elevated post-injury.
Emily Horner +14 more
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Resistin as Modulator of Functional Activity of Phagocytes in Colostrum and Blood of Overweight and Obese Mothers [PDF]
BiomedicinesBackground/Objectives: Resistin is an adipokine involved in obesity pathogenesis, but its effects on blood and colostrum immune cells from obese mothers remain unclear.
Carla Roberta Silva Souza Antônio +9 more
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Frontiers in Immunology, 2021 BackgroundResistin is an endogenous ligand of Toll-like receptor 4 that activates several inflammatory signals. But the physiological function of resistin in community-acquired pneumonia (CAP) remains unknown. The goal of this research was to explore the
Chun-Mei Feng +7 more
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Frontiers in Nutrition, 2022 BackgroundSarcopenia is common in patients with chronic obstructive pulmonary disease (COPD) and is mainly caused by systemic inflammation. Resistin acts as a proinflammatory cytokine and is involved in the activation of multiple inflammatory signaling ...
Jinghan Gao +13 more
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Resistin production from adipose tissue is decreased in db/db obese mice, and is reversed by rosiglitazone. [PDF]
PLoS ONE, 2013 OBJECTIVE: This study was designed to (1) investigate the expression profiles of resistin in db/db mice and its dynamic association with metabolic parameters; and (2) evaluate the effects of Rosiglitazone on production of resistin.
Hongying Ye +3 more
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Resistin increases monolayer permeability of human coronary artery endothelial cells. [PDF]
PLoS ONE, 2013 Resistin has been linked to obesity, insulin resistance, atherosclerosis, and the development of cardiovascular disease. Nevertheless, the effects and the molecular mechanisms of resistin on endothelial permeability, a key event in the development of ...
Md Saha Jamaluddin +5 more
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Resistin Contribution to Cardiovascular Risk in Chronic Kidney Disease Male Patients
Cells, 2023 Background: Resistin is a molecule that belongs to the Resistin-Like Molecules family (RELMs), the group of proteins taking part in inflammatory processes. Increased resistin concentrations are observed in cardiovascular complications.
Katarzyna Romejko +5 more
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The current biology of resistin [PDF]
Journal of Internal Medicine, 2004 Abstract.Obesity and noninsulin‐dependent diabetes mellitus are globally epidemic. Insulin resistance is a major contributor to the pathogenesis of type II diabetes and plays a role in numerous other metabolic disorders including hypertension, dyslipidaemia and atherosclerosis.
Claire M, Steppan, Mitchell A, Lazar
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Resistin production does not affect outcomes in a mouse model of acute surgical sepsis
PLoS ONE, 2022 Introduction Because of the strong correlation between the blood concentration of circulating resistin and the illness severity of septic patients, resistin has been proposed as a mediator of sepsis pathophysiology.
Anthony S. Bonavia +3 more
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