Results 61 to 70 of about 3,694,925 (238)

Diagnosis of Polycystic Ovarian Syndrome on Doppler Based Resistive Index and Pulsatility Index

Journal of Rawalpindi Medical College, 2016
Background: To determine Doppler based mean Pulsatility index and mean Resistive index in patient diagnosed with polycystic ovary syndrome. Methods: In this cross sectional study one hundred and twenty patients with clinical diagnosis of polycystic Ovary
Asma Bano
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Randomized controlled study on resistive vibration exercise (EVE Study): protocol, implementation and feasibility [PDF]

, 2013
A training intervention comparing resistance exercise with or without whole-body vibration (WBV) was conducted to compare acute and chronic effects on functional and molecular parameters.
Weber, Tobias, Bloch, W., Zange, Jochen, May, F., Rittweger, Jörn, Rosenberger, André, Mester, J., Beijer, Asa, Schoenau, Eckhardt   +8 more
core  

Fatty acid binding proteins1/2 and their correlation with renal doppler ultrasound resistive index as predictors of diabetic kidney disease in T2DM patients

The Egyptian Journal of Internal Medicine
Background Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease and end-stage renal disease worldwide. Fatty acid-binding proteins (FABP1 and FABP2) have emerged as potential biomarkers of renal injury.
Amr Ahmed El Sayed El Santawy, Medhat Abd El Megeid Ghazy, Tamer El Saeed Haydara, Ahmed Ibrahem Ebeed, Amr Khalifa Hussien   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Fault modelling and accelerated simulation of integrated circuits manufacturing defects under process variation

, 2013
As silicon manufacturing process scales to and beyond the 65-nm node, process variation can no longer be ignored. The impact of process variation on integrated circuit performance and power has received significant research input.
Zhong, Shida
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Renal resistive index (mean, 95% CI) for patients without AKI and patients developing AKI (A) renal resistive index (mean, 95% CI) for the different stages of AKI (B).

, 2018
Renal resistive index (mean, 95% CI) for patients without AKI and patients developing AKI (A) renal resistive index (mean, 95% CI) for the different stages of AKI (B).
Monique C. de Waard (193614), Heleen M. Oudemans-van Straaten (5345840), Jelle L. G. Haitsma Mulier (5368073), Pieter Roel Tuinman (5368058), Angelique M. E. Spoelstra-de Man (5368061), Paul W. G. Elbers (5368067), Sander Rozemeijer (5368064), Jantine G. Röttgering (5368070)   +7 more
core   +1 more source

Correlation of Duplex Ultrasonographic Parameters with Glomerular Filtration Rate in Chronic Kidney Disease

Journal of Nepal Health Research Council, 2019
Background: Chronic kidney disease encompasses a spectrum of different pathophysiological processes associated with abnormal renal function and a progressive decline in glomerular filtration rate. Duplex ultrasonography is widely available and important
Karun Devkota, Mukesh Kumar Gupta, Ashok Raj Pant, Prahlad Karki   +3 more
doaj   +1 more source