Results 241 to 250 of about 351,150 (284)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Near-surface geophysical and sedimentological analyses for the lower havel inner delta - a dataset of the floodplain lithostratigraphy. [PDF]

open access: yesData Brief
Köhler A   +7 more
europepmc   +1 more source

Reply to: "Comment on volcanic monitoring of the 2021 La Palma eruption using long-period magnetotelluric data". [PDF]

open access: yesSci Rep
Piña-Varas P   +7 more
europepmc   +1 more source

Strain Tuning of Weyl Nodes in SrRuO<sub>3</sub> Membranes. [PDF]

open access: yesNano Lett
Blah P   +11 more
europepmc   +1 more source

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