Results 71 to 80 of about 351,150 (284)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Variation of the Electrical Resistivity of Peruvian Tropical Woods
This study investigated the electrical resistivity of 105 timber species from the Peruvian tropical forest; with a focus on promoting sustainable use by considering the wood’s equilibrium moisture content (EMC).
Emer Ronald Rosales Solórzano +6 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Contactless Tracking of Decomposition in Self‐Reporting Ceramic Cr‐Al‐B Coatings
Autonomous health tracking of coated components via electrical resistance measurements requires physical connections between coating and readout. Here, the proof of concept for contactless tracking of decomposition in autonomous self‐reporting Cr‐Al‐B ...
Peter J. Pöllmann +13 more
doaj +1 more source
On-sample water content measurement for a complete local monitoring in triaxial testing of unsaturated soils [PDF]
To provide a complete local monitoring of the state of an unsaturated soil sample during triaxial testing, a local water content measurement device was adapted to a triaxial device comprising the measurement of local displacements (Hall effect ...
Cui, Yu-Jun +3 more
core +6 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The influence of changes in water content on the electrical resistivity of a natural unsaturated loess [PDF]
Non-destructive methods of measuring water content in soils have been extensively developed in the last decades, especially in soil science. Among these methods, the measurements based on the electrical resistivity are simple and reliable thanks to the ...
Cui, Yu Jun +3 more
core +3 more sources

