Results 131 to 140 of about 11,688 (211)

The intrinsic macrolide resistome of Escherichia coli

Antimicrobial Agents and Chemotherapy
ABSTRACT Intrinsic resistance to macrolides in Gram-negative bacteria is primarily attributed to the low permeability of the outer membrane, though the underlying genetic and molecular mechanisms remain to be fully elucidated.
Yibing Ma, Mattia Pirolo, Bimal Jana, Viktor Hundtofte Mebus, Luca Guardabassi   +4 more
openaire   +4 more sources

Teredinibacter resistome.

, 2018
A) resistome PCA using the fifteen most important genes based on mean decrease accuracy of Random Forest analysis. Teredinibacter forms a major group influenced by polyamine, isoniazid, and PK-NRP-derived antibiotics.
Amanda B. Campos (5963054), Bas E. Dutilh (118607), Gabriella B. Ribeiro (5963063), Amaro E. Trindade-Silva (153934), F. A. Bastiaan von Meijenfeldt (5963057), Genivaldo G. Z. Silva (153950), Diego V. Wilke (1596718), Julio P. Daniel (5963060), Thais L. Brito (5963051), Pedro M. Meirelles (160004), Daniela T. de Moraes (5963066)   +10 more
core   +1 more source

The variation of resistome, mobilome and pathogen in domestic and industrial wastewater treatment systems

Environment International
Wastewater treatment plants (WWTPs), including both domestic and industrial facilities, are key contributors to antibiotic resistance genes (ARGs) and human pathogens in the environment.
Jiayu Chen, Zhiguo Su, Feifei Li, Feng Cao, Fuzhong Xiong, Bo Jiang, Yi Xing, Donghui Wen   +7 more
doaj   +1 more source

Breastfeeding and early Bifidobacterium-driven microbial colonization shape the infant gut resistome

Nature Communications
The assembly of the gut resistome in early life is key to infant health. Specific perinatal factors such as cesarean section (C-section), antibiotic exposure and lack of breastfeeding practices are detrimental to proper microbial development and increase
Anna Samarra, Alejandro J. Alcañiz, Cecilia Martínez-Costa, Alberto Marina, Iñaki Comas, Nicola Segata, Narciso M. Quijada, Maria Carmen Collado   +7 more
doaj   +1 more source

Oropharyngeal resistome remains stable during COVID-19 therapy, while fecal resistome shifts toward a less diverse resistotype

Summary: Antimicrobial resistance poses a serious threat to global public health. The COVID-19 pandemic underscored the need to monitor the dissemination of antimicrobial resistance genes and understand the mechanisms driving this process. In this study,
Mikhail K. Devkota, Aleksey K. Fomenko, Yulia S. Galeeva, Ivan E. Kozlov, Maxim D. Morozov, Igor V. Maev, Dmitry N. Andreev, Vladimir V. Evdokimov, Vadim M. Govorun, Filipp S. Sokolov, Alexander I. Manolov, Nikolai G. Andreev, Anna S. Speranskaya, Evgenii I. Olekhnovich, Elena N. Ilina, Ksenia M. Klimina, Andrey V. Zaborovsky, Sergei V. Tsaregorodtsev, Dmitry E. Fedorov, Vladimir A. Veselovsky, Polina Y. Zoruk, Petr A. Bely, Elena V. Korneenko, Alexander V. Pavlenko, Natella I. Krikheli, Oleg O. Yanushevich, Elizaveta V. Starikova, Daria I. Boldyreva, Oleg V. Levchenko, Oksana V. Selezneva   +29 more
core   +1 more source

The hidden resistome of retail chicken meat [PDF]

Journal of Global Antimicrobial Resistance, 2015
Gregory C.A. Amos, Abigail Carter, Peter M. Hawkey, William H. Gaze, Elizabeth M. Wellington   +4 more
openaire   +2 more sources

Dynamics of Infant Gut Resistome and Mobilome: Impact of Gestational Age, Antibiotics, Probiotics, and Other Early-Life Factors

Antimicrobial resistance (AMR) is a growing global health concern, particularly in vulnerable populations such as infants. The gut microbiota, which plays a crucial role in health and disease, is shaped by early-life factors like birth mode, feeding type,
Bargheet, Ahmed
core  

Exploring the Ciprofloxacin Resistome

, 2018
This thesis presents an exploration of the resistance evolution in Escherichia coli towards the antibiotic ciprofloxacin. High level ciprofloxacin resistance is typically acquired by an accumulation of mutations and plasmid borne genes reducing drug target binding, increasing drug efflux, and modifying the drug. Paper I describes the finding that novel
openaire   +1 more source

Pangenomics insights of enterococcus faecium human isolates and identification of novel therapeutic targets by in silico subtractive genomics. [PDF]

Braz J Microbiol
Mascarenhas YVC, Felice AG, Zen FL, Ceballos VAS, de Castro Soares S.   +4 more
europepmc   +1 more source

Bioinformatic Resistome Profiling of Metal Tolerance Mechanisms in Endodontic Infections: Implications for Antimicrobial Nanoparticle-Based Biomaterials. [PDF]

J Funct Biomater
Luna-Lara CA, Luna-Dominguez CR, Oliver-Parra R, Criollo-Barrios OV, Vaca-Jasso MLD, Salas-Orozco MF.   +5 more
europepmc   +1 more source