Results 111 to 120 of about 11,619 (200)

Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome

Nature Medicine
Doxycycline post-exposure prophylaxis (doxy-PEP) reduces bacterial sexually transmitted infections among men who have sex with men and transgender women.
Victoria T. Chu, Abigail L. Glascock, Deborah Donnell, Cole Grabow, Clare E. Brown, Ryan Ward, Christina Love, Katrina L Kalantar, Stephanie E. Cohen, Chase Cannon, Michael H. Woodworth, Colleen F Kelley, Connie Celum, A. Luetkemeyer, C. Langelier   +14 more
semanticscholar   +1 more source

Endogenous CRISPR‐Based Removal of Tetracycline Resistance in Bifidobacterium animalis subsp. lactis Through a Safe‐by‐Design Approach

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
Endogenous CRISPR–Cas editing was used to inactivate tetW gene in Bifidobacterium animalis subsp. lactis. The engineered strain showed reduced tetracycline resistance while retaining key probiotic traits and genetic stability. This work demonstrates a Safe‐by‐Design strategy for engineering safer industrial probiotics and mitigating antimicrobial ...
Marianna Bozzetti, Matteo Raneri, Claudia Cortimiglia, Giovanni Milani, Federica Volontè, Franco Lucchini, Daniela Bassi, Pier Sandro Cocconcelli   +7 more
wiley   +1 more source

Spatio‐temporal characteristics of the gastrointestinal resistome in a cow‐to‐calf model and its environmental dissemination in a dairy production system

iMeta
Microbiome and resistome transmission from mother to child, as well as from animal to environment, has been widely discussed in recent years. Dairy cows mainly provide milk and meat.
Shuai Liu, Yi-Min Zhuang, Tian-Yu Chen, Duo Gao, Jianxin Xiao, Jinfeng Wang, Jinghui Li, Xin-Jie Zhao, Rong Peng, Wenli Guo, Jia-Lin Wei, Mo Sha, Jing-Jun Wang, Jia-Ying Ma, Mei Ma, Mengmeng Li, Wei Wang, Yajing Wang, Sheng-Li Li, Zhijun Cao   +19 more
semanticscholar   +1 more source

Antimicrobial Resistance at the Human–Animal–Environment Interface: A One Health Perspective on Drivers, Transmission, and Public Health Responses

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Antimicrobial resistance (AMR) is a global health threat driven by interconnected antimicrobial use and environmental pressures across human, animal, and ecological systems. This review synthesizes current evidence on the major drivers, transmission pathways, reservoirs, surveillance challenges, and public health responses ...
Nurshad Ali
wiley   +1 more source

Exploring the aquatic resistome [PDF]

, 2019
Antibiotic resistance is one of the major problems in public health today since the failure of antibiotherapy has dramatic clinical implications such as the increase of mobility/mortality and of health costs.
Menezes, Carina, Paulo, Octávio, Ferreira, Eugénia, Dias, Elsa, Rosado, Tânia, Caniça, Manuela, Manageiro, Vera, Balata, Duarte   +7 more
core  

Viral metagenome reveals microbial hosts and the associated antibiotic resistome on microplastics

Nature Water
Microplastics provide a unique niche for viruses, promoting viral interactions with hosts and accelerating the rapid ‘horizontal’ spread of antibiotic resistance genes (ARGs).
Ruilong Li, Xin-Li An, Yi-Jin Wang, Zhu-Gen Yang, Jian-Qiang Su, Jonathan M. Cooper, Yong-Guan Zhu   +6 more
semanticscholar   +1 more source

Maternal and infant gut microbiome

iMeta, Volume 5, Issue 4, August 2026.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance [PDF]

, 2009
The ardA gene, found in many prokaryotes including important pathogenic species, allows associated mobile genetic elements to evade the ubiquitous Type I DNA restriction systems and thereby assist the spread of resistance genes in bacterial populations ...
Blakely, Garry W., Dryden, David T. F., White, John H., McMahon, Stephen A., Cooper, Laurie P., Naismith, James H., Roberts, Gareth A., Liu, Huanting, Oke, Muse, Naismith, James Henderson, Carter, Lester G., Sanghvi, Bansi, Walkinshaw, Malcolm D., Johnson, Kenneth A.   +13 more
core   +1 more source

Industrial effluents boosted antibiotic resistome risk in coastal environments

, 2023
Wastewater treatment plants (WWTPs) have been regarded as an important source of antibiotic resistance genes (ARGs) in environment, but out of municipal domestic WWTPs, few evidences show how environment is affected by industrial WWTPs.
Zhiguo Su, Donghui Wen, Yuhan Zheng, Yushi Tang, Lyujun Chen, April Z. Gu   +5 more
core   +1 more source

Seasonal Restructuring of Microbial Communities and Resistomes in the Shitalakshya River, Bangladesh Revealed by Shotgun Metagenomics

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque, Md. Shaminur Rahman, Munawar Sultana, Anowara Begum   +3 more
wiley   +1 more source