Results 101 to 110 of about 4,279,285 (309)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Ohio Commission on Dispute Resolution and Conflict Management

open access: yes
The Ohio Commission on Dispute Resolution and Conflict Management has closed effective June 30, 2011.; World Wide Web Resource; The mission of the Ohio Commission on Dispute Resolution and Conflict Management, which is based in Columbus, Ohio, is to ...

core  

Conflicts and Political Instability in Sudan: A Re-visit Discourse

open access: yesInternational Studies Journal, 2022
The research study evaluated the nature and character of the Darfur crisis of Sudan. The study made used of only secondary source of data, exploring various literatures on the issue from scholars.
Efe Ann Ijoyah
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

An Introduction to Metals Stabilization for Site Remediation

open access: yesRevista Águas Subterrâneas, 2013
A estabilização de metais no solo e águassubterrâneas pode ser um componente integral da remediação . Tecnologias de estabilização pode ser aplicado para minimizar os custos de eliminação de ex-situ solo ou de resíduos, que podem ser reutilizados no ...
Lowell Gerardo Kessel, Bernd W. Rehm
doaj  

Efficient cation separation based on humidity control and adsorption

open access: yesNature Communications
Precise ion sieving techniques are of great importance in various fields including the energy and environment. However, existing extraction methods, often associated with environmental risks, are lack of selectivity, time-consuming, and high cost.
Jinjiang Liang   +16 more
doaj   +1 more source

¿Más mujeres árbitros? La equidad de género en los tribunales arbitrales

open access: yesThēmis, 2020
A lo largo de las últimas décadas se han diseñado, presentado e implementado diversas iniciativas públicas y privadas dirigidas a disminuir las brechas de género en distintos escenarios profesionales, promoviendo así la progresiva inclusión de las ...
Tatiana Herrada Sánchez
doaj  

Resolutions—Resolutions [PDF]

open access: yesJournal of the American Society of Echocardiography, 2016
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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